It is suggested that thymus-dependent (T) lymphocytes play a key role in preventing
autoimmunity, and that this is achieved by two mechanisms. First, T-lymphocytes are …

The neurological complications of Behçet's syndrome have not been characterized with
clarity. We present the clinical features, imaging characteristics and CSF findings of a series …

Objective. To contribute to knowledge of vascular occlusion in Behçet's disease (BD),
prevalence and relative risk for thrombosis were ascertained retrospectively in a cohort of …

Acyclovir is a potent antiviral drug, of proven efficacy in the treatment of herpes simplex virus
infection. Since this virus has been implicated in the aetiology of Behcçet's syndrome, the …

Anticardiolipin antibodies have recently been described in association with arterial and
venous thrombosis, and with neurological symptoms, in connective tissue diseases. In a …

Twelve patients with active Behçet's uveitis with marked deterioration of visual acuity in at
least one eye were treated with cyclosporin A (CyA). An initial improvement in the severity of …

There is a high incidence of acute myeloid leukaemia in patients who have been treated
with chlorambucil. This appears at least in part to be directly due to the drug itself and cannot …

Cytotoxic drugs suppress many forms of immune and inflammatory response in animals
(Gabrielsen and Good, 1967). It has been argued that their immunosuppressive properties …

Lymphocytes in the blood and central lymphoid tissues participate in a variety of host
defence mechanisms against virus infections. These include cell-mediated reactions against …

Three patients with angina pectoris treated with practolol in varying doses developed a
syndrome of arthralgia, particularly of the small joints of the hands, rash, fever, a raised ESR …