Haematological complications are frequently seen in SLE. Anaemia, leucopenias and
thrombocytopenia may result from bone marrow failure or excessive peripheral cell …

Objective. To assess the short‐term urate‐lowering effect of fenofibrate in men on long‐term
allopurinol therapy for hyperuricaemia and gout. Methods. Ten male patients (38–74 yr) with …

Objectives. Fcaγ and complement receptors play an important role in the interaction
between immune complexes (IC) and monocytes/macrophages. Recent work has …

The name lupus, derived from the Latin for wolf, was used first as a medical term by
Rogerius (c. 1230) and later by Paracelsus (1493±1541) and Sennert (1611). A more …

An increase in leucocyte apoptosis and impaired clearance of apoptotic cells has been
observed in patients with systemic lupus erythematosus (SLE). Apoptotic cells are likely to …

Abnormal clearance by the mononuclear phagocytic system of immune complexes (IC) is
important in the pathogenesis of systemic lupus erythematosus (SLE). We have developed …

I read with great interest Dr Jawad's letter and the authors' reply about the EULAR
recommendations for the management of knee osteoarthritis (OA). 1 2 As a member of the …

Osteoporosis is responsible for a significant burden both individually and socially, but is
readily treated with antiresorptive agents and mineral supplementation. However, long-term …

Short-term studies with fenofibrate, an established treatment for hyperlipidaemia, have
shown that its unique side effect of urate lowering is mediated through enhanced renal urate …

We read with interest the report by Drynda et al demonstrating that treatment of rheumatoid
arthritis (RA) with anti-tumour necrosis factor α (anti-TNFα) induces subtle changes in the …