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2013 1
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Page 1
OX40L Inhibition Suppresses KLH-driven Immune Responses in Healthy Volunteers: A Randomized Controlled Trial Demonstrating Proof-of-Pharmacology for KY1005.
Saghari M, Gal P, Gilbert S, Yateman M, Porter-Brown B, Brennan N, Quaratino S, Wilson R, Grievink HW, Klaassen ES, Bergmann KR, Burggraaf J, van Doorn MBA, Powell J, Moerland M, Rissmann R. Saghari M, et al. Among authors: porter brown b. Clin Pharmacol Ther. 2022 May;111(5):1121-1132. doi: 10.1002/cpt.2539. Epub 2022 Mar 1. Clin Pharmacol Ther. 2022. PMID: 35092305 Free PMC article. Clinical Trial.
Safety and efficacy of amlitelimab, a fully human nondepleting, noncytotoxic anti-OX40 ligand monoclonal antibody, in atopic dermatitis: results of a phase IIa randomized placebo-controlled trial.
Weidinger S, Bieber T, Cork MJ, Reich A, Wilson R, Quaratino S, Stebegg M, Brennan N, Gilbert S, O'Malley JT, Porter-Brown B. Weidinger S, et al. Among authors: porter brown b. Br J Dermatol. 2023 Oct 25;189(5):531-539. doi: 10.1093/bjd/ljad240. Br J Dermatol. 2023. PMID: 37463508 Free article. Clinical Trial.
Effect of tocilizumab on neutrophils in adult patients with rheumatoid arthritis: pooled analysis of data from phase 3 and 4 clinical trials.
Moots RJ, Sebba A, Rigby W, Ostor A, Porter-Brown B, Donaldson F, Dimonaco S, Rubbert-Roth A, van Vollenhoven R, Genovese MC. Moots RJ, et al. Among authors: porter brown b. Rheumatology (Oxford). 2017 Apr 1;56(4):541-549. doi: 10.1093/rheumatology/kew370. Rheumatology (Oxford). 2017. PMID: 28013198 Free PMC article. Review.
Effects of tocilizumab on neutrophil function and kinetics.
Lok LSC, Farahi N, Juss JK, Loutsios C, Solanki CK, Peters AM, Donaldson F, Porter-Brown B, Chilvers ER. Lok LSC, et al. Among authors: porter brown b. Eur J Clin Invest. 2017 Oct;47(10):736-745. doi: 10.1111/eci.12799. Epub 2017 Aug 31. Eur J Clin Invest. 2017. PMID: 28796316 Free article. Clinical Trial.
Malignancy rates in patients with rheumatoid arthritis treated with tocilizumab.
Rubbert-Roth A, Sebba A, Brockwell L, Kelman A, Porter-Brown B, Pulley J, Napalkov P, van Vollenhoven RF. Rubbert-Roth A, et al. Among authors: porter brown b. RMD Open. 2016 May 10;2(1):e000213. doi: 10.1136/rmdopen-2015-000213. eCollection 2016. RMD Open. 2016. PMID: 27252893 Free PMC article.
Neutropenia During Tocilizumab Treatment Is Not Associated with Infection Risk in Systemic or Polyarticular-course Juvenile Idiopathic Arthritis.
Pardeo M, Wang J, Ruperto N, Alexeeva E, Chasnyk V, Schneider R, Horneff G, Huppertz HI, Minden K, Onel K, Zemel L, Martin A, Koné-Paut I, Siamopoulou-Mavridou A, Silva CA, Porter-Brown B, Bharucha KN, Brunner HI, De Benedetti F; Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG). Pardeo M, et al. Among authors: porter brown b. J Rheumatol. 2019 Sep;46(9):1117-1126. doi: 10.3899/jrheum.180795. Epub 2019 Mar 1. J Rheumatol. 2019. PMID: 30824645 Free article.
Tocilizumab in rheumatoid arthritis: a case study of safety evaluations of a large postmarketing data set from multiple data sources.
Curtis JR, Perez-Gutthann S, Suissa S, Napalkov P, Singh N, Thompson L, Porter-Brown B; Actemra Pharmacoepidemiology Board. Curtis JR, et al. Among authors: porter brown b. Semin Arthritis Rheum. 2015 Feb;44(4):381-8. doi: 10.1016/j.semarthrit.2014.07.006. Epub 2014 Jul 27. Semin Arthritis Rheum. 2015. PMID: 25300699 Free article.