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Nuclear antigen-reactive CD4+ T cells expand in active systemic lupus erythematosus, produce effector cytokines, and invade the kidneys.
Kidney Int. 2021 Jan;99(1):238-246. doi: 10.1016/j.kint.2020.05.051. Epub 2020 Jun 24.
Kidney Int. 2021.
PMID: 32592813
Free article.
Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods.
Tesch S, Abdirama D, Grießbach AS, Brand HA, Goerlich N, Humrich JY, Bacher P, Hiepe F, Riemekasten G, Enghard P.
Tesch S, et al. Among authors: abdirama d.
Sci Rep. 2020 Dec 4;10(1):21312. doi: 10.1038/s41598-020-78223-3.
Sci Rep. 2020.
PMID: 33277543
Free PMC article.
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Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus.
von Spee-Mayer C, Siegert E, Abdirama D, Rose A, Klaus A, Alexander T, Enghard P, Sawitzki B, Hiepe F, Radbruch A, Burmester GR, Riemekasten G, Humrich JY.
von Spee-Mayer C, et al. Among authors: abdirama d.
Ann Rheum Dis. 2016 Jul;75(7):1407-15. doi: 10.1136/annrheumdis-2015-207776. Epub 2015 Aug 31.
Ann Rheum Dis. 2016.
PMID: 26324847
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Low-dose interleukin-2 therapy in refractory systemic lupus erythematosus: an investigator-initiated, single-centre phase 1 and 2a clinical trial.
Humrich JY, von Spee-Mayer C, Siegert E, Bertolo M, Rose A, Abdirama D, Enghard P, Stuhlmüller B, Sawitzki B, Huscher D, Hiepe F, Alexander T, Feist E, Radbruch A, Burmester GR, Riemekasten G.
Humrich JY, et al. Among authors: abdirama d.
Lancet Rheumatol. 2019 Sep;1(1):e44-e54. doi: 10.1016/S2665-9913(19)30018-9. Epub 2019 Aug 28.
Lancet Rheumatol. 2019.
PMID: 38229359
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