Abstract
We describe a 61-year-old male patient who was treated with allopurinol and developed fever, a skin rash, eosinophilia and severe renal and liver dysfunction. We discuss the allopurinol hypersensitivity syndrome as a serious complication of the use of allopurinol, and briefly review the aetiology, prevention and treatment modalities.
MeSH terms
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Acute Kidney Injury / diagnosis
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Acute Kidney Injury / drug therapy
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Acute Kidney Injury / etiology
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Allopurinol / adverse effects*
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Anti-Inflammatory Agents / therapeutic use
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Diagnosis, Differential
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Drug Hypersensitivity / diagnosis
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Drug Hypersensitivity / etiology*
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Gout / drug therapy
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Gout Suppressants / adverse effects*
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Humans
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Male
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Middle Aged
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Prednisone / therapeutic use
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Syndrome
Substances
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Anti-Inflammatory Agents
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Gout Suppressants
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Allopurinol
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Prednisone