Iatrogenic nerve injuries are an undesired byproduct of the practice of medicine and have been so since antiquity. The majority of such injuries occur perioperatively, and are, therefore, attributed to surgeons and anesthesiologists. Nonetheless, the members of almost every clinical specialty are at risk to some degree. Iatrogenic nerve injuries can affect almost any portion of the peripheral nervous system, and can result from many different causes. This article reviews many of the more common iatrogenic nerve lesions.