Sjögren's syndrome with acute renal failure caused by renal pseudolymphoma

P Cacoub; C Ginsburg; Z Tazi; H Beaufils; F Charlotte; F Davi; P Carde; P Godeau

doi:10.1016/s0272-6386(96)90262-0

Sjögren's syndrome with acute renal failure caused by renal pseudolymphoma

Am J Kidney Dis. 1996 Nov;28(5):762-6. doi: 10.1016/s0272-6386(96)90262-0.

Authors

P Cacoub¹, C Ginsburg, Z Tazi, H Beaufils, F Charlotte, F Davi, P Carde, P Godeau

Affiliation

¹ Department of Internal Medicine, Hopital de La Pitié-Salpêtrière, Paris, France.

PMID: 9158218
DOI: 10.1016/s0272-6386(96)90262-0

Abstract

A 56-year-old man with Sjögren's syndrome was found to have acute renal failure. Immunopathologic analysis of renal biopsy specimens showed polyclonal lymphocytic interstitial infiltration. DNA analysis of the T-cell receptor and the heavy chain immunoglobulin genes showed a polyclonal pattern of gene rearrangements. Renal failure caused by this pseudolymphoma regressed dramatically with steroid therapy. This is the first reported case of proven renal pseudolymphoma that regressed with steroid therapy.

Publication types

Case Reports

MeSH terms

Acute Kidney Injury / drug therapy
Acute Kidney Injury / etiology*
Glucocorticoids / therapeutic use
Humans
Kidney / pathology
Kidney Neoplasms / complications*
Kidney Neoplasms / drug therapy
Kidney Neoplasms / pathology
Leukemia, Lymphocytic, Chronic, B-Cell / complications*
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
Male
Methylprednisolone / therapeutic use
Middle Aged
Prednisone / therapeutic use
Sjogren's Syndrome / complications*

Substances

Glucocorticoids
Prednisone
Methylprednisolone