Abstract
We describe 2 patients in whom a sustained remission of longstanding rheumatoid arthritis occurred with treatment for acute myelogenous leukemia (cytosine arabinoside, daunorubicin, and m-AMSA), even though both illnesses had been refractory to therapy with standard disease-modifying agents. These 2 patients represent the first successful treatment of rheumatoid disease using such an approach.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amsacrine / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Arthritis, Rheumatoid / complications
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Arthritis, Rheumatoid / drug therapy*
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Cytarabine / administration & dosage
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Daunorubicin / administration & dosage
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Female
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Humans
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Leukemia, Myeloid, Acute / complications
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Leukemia, Myeloid, Acute / drug therapy*
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Middle Aged
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Remission Induction
Substances
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Amsacrine
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Cytarabine
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Daunorubicin