The leucocyte L1 protein: identity with the cystic fibrosis antigen and the calcium-binding MRP-8 and MRP-14 macrophage components

K B Andersson; K Sletten; H B Berntzen; I Dale; P Brandtzaeg; E Jellum; M K Fagerhol

doi:10.1111/j.1365-3083.1988.tb02437.x

The leucocyte L1 protein: identity with the cystic fibrosis antigen and the calcium-binding MRP-8 and MRP-14 macrophage components

Scand J Immunol. 1988 Aug;28(2):241-5. doi: 10.1111/j.1365-3083.1988.tb02437.x.

Authors

K B Andersson¹, K Sletten, H B Berntzen, I Dale, P Brandtzaeg, E Jellum, M K Fagerhol

Affiliation

¹ Department of Biochemistry, University of Oslo, Norway.

PMID: 3413449
DOI: 10.1111/j.1365-3083.1988.tb02437.x

Abstract

The partial amino acid sequence of L1 protein light and heavy chains reveals an overall structure identical to the two macrophage proteins, MRP-8 and MRP-14, deduced from the sequence of the cDNA encoding the polypeptides. The light chain of L1 protein (L1-L) was shown to contain two modified amino acid residues.

MeSH terms

Amino Acid Sequence
Antigens, Surface / analysis*
Chemical Phenomena
Chemistry
Cystic Fibrosis / blood
Cystic Fibrosis / immunology
Humans
Leukocyte L1 Antigen Complex
Macrophages
Molecular Sequence Data
Peptide Fragments / analysis

Substances

Antigens, Surface
Leukocyte L1 Antigen Complex
Peptide Fragments