Elevated serum beta-2-microglobulin--a prognostic marker for development of AIDS among patients with persistent generalized lymphadenopathy

J Morfeldt-Månson; I Julander; L V von Stedingk; J Wasserman; B Nilsson

doi:10.1007/BF01644315

Elevated serum beta-2-microglobulin--a prognostic marker for development of AIDS among patients with persistent generalized lymphadenopathy

Infection. 1988 Mar-Apr;16(2):109-10. doi: 10.1007/BF01644315.

Authors

J Morfeldt-Månson¹, I Julander, L V von Stedingk, J Wasserman, B Nilsson

Affiliation

¹ Department of Infectious Diseases, Roslagstull Hospital, Karolinska Institute, Stockholm.

PMID: 3286507
DOI: 10.1007/BF01644315

Abstract

For evaluation of its prognostic value, the level of serum beta-2-microglobulin was determined in early serum samples from 88 patients with persistent generalized lymphadenopathy in a prospective longitudinal study. Patients with serum beta-2-microglobulin greater than 2.6 mg/l were found to have a significantly higher risk of developing AIDS earlier when compared to patients with a lower level (p less than 0.001).

MeSH terms

AIDS-Related Complex / blood*
Acquired Immunodeficiency Syndrome / diagnosis*
Humans
Longitudinal Studies
Prognosis
Prospective Studies
Risk Factors
Time Factors
beta 2-Microglobulin / analysis*

Substances

beta 2-Microglobulin