Abstract
Using a monospecific rabbit antibody against Yersinia enterocolitica outer membrane protein 1, we examined synovial biopsy specimens from 7 patients with Yersinia-induced arthritis. Yersinia were demonstrated in the synovial membrane by indirect immunofluorescence in 4 patients with Yersinia-induced arthritis, but not in 6 control patients with Salmonella-induced arthritis or with rheumatoid arthritis. These findings suggest the persistence of Yersinia in the joints of patients with Yersinia-induced arthritis.
MeSH terms
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Adult
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Antigens, Bacterial / immunology
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Arthritis, Infectious / immunology
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Arthritis, Infectious / microbiology*
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Arthritis, Infectious / pathology
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Biopsy
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Female
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Fluorescent Antibody Technique
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Humans
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Male
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Middle Aged
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Synovial Membrane / immunology
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Synovial Membrane / microbiology*
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Synovial Membrane / pathology
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Yersinia Infections / immunology
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Yersinia Infections / pathology
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Yersinia enterocolitica / immunology
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Yersinia enterocolitica / isolation & purification*
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Yersinia enterocolitica / ultrastructure