Etanercept-induced lupus erythematosus presenting as a unilateral pleural effusion

Jafar Abunasser; Faripour A Forouhar; Mark L Metersky

doi:10.1378/chest.08-0034

Etanercept-induced lupus erythematosus presenting as a unilateral pleural effusion

Chest. 2008 Oct;134(4):850-853. doi: 10.1378/chest.08-0034.

Authors

Jafar Abunasser¹, Faripour A Forouhar², Mark L Metersky³

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington, CT.
² Department of Anatomic Pathology and Laboratory Medicine, University of Connecticut School of Medicine, Farmington, CT.
³ Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington, CT. Electronic address: Metersky@nso.uchc.edu.

PMID: 18842918
DOI: 10.1378/chest.08-0034

Abstract

A 72-year-old man receiving etanercept for the treatment of psoriatic arthritis had an exudative pleural effusion with nonspecific fluid analysis and pleural biopsy findings. He was ultimately found to have drug-induced lupus erythematosus due to the etanercept. The spectrum of autoimmune disease due to the use of tumor necrosis factor inhibitors is reviewed.

Publication types

Case Reports

MeSH terms

Aged
Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
Etanercept
Humans
Immunoglobulin G / adverse effects*
Lupus Erythematosus, Systemic / chemically induced*
Lupus Erythematosus, Systemic / diagnosis*
Lupus Erythematosus, Systemic / therapy
Male
Pleural Effusion / etiology*
Pleural Effusion / pathology
Pleural Effusion / therapy
Receptors, Tumor Necrosis Factor

Substances

Anti-Inflammatory Agents, Non-Steroidal
Immunoglobulin G
Receptors, Tumor Necrosis Factor
Etanercept