Molecular ablation of transforming growth factor beta signaling pathways by tyrosine kinase inhibition: the coming of a promising new era in the treatment of tissue fibrosis

Arthritis Rheum. 2008 Aug;58(8):2219-24. doi: 10.1002/art.23634.
No abstract available

Publication types

  • Comment
  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Extracellular Matrix / physiology
  • Fibrosis / therapy
  • Humans
  • Kidney Diseases / drug therapy*
  • Kidney Diseases / physiopathology
  • Protein Kinase Inhibitors / therapeutic use*
  • Protein-Tyrosine Kinases / antagonists & inhibitors*
  • Pulmonary Fibrosis / drug therapy*
  • Pulmonary Fibrosis / physiopathology
  • Scleroderma, Systemic / drug therapy*
  • Scleroderma, Systemic / physiopathology
  • Signal Transduction / drug effects*
  • Signal Transduction / physiology
  • Transforming Growth Factor beta / physiology*

Substances

  • Protein Kinase Inhibitors
  • Transforming Growth Factor beta
  • Protein-Tyrosine Kinases