Abstract
Two cases are presented in which repeated use of the TNF-alpha blocker infliximab may have led to development of pustular skin lesions. These findings might result in an improved understanding regarding the safety of infliximab with long-term usage.
MeSH terms
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Adult
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Antibodies, Monoclonal / adverse effects*
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Antibodies, Monoclonal / therapeutic use
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Antirheumatic Agents / adverse effects*
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Antirheumatic Agents / therapeutic use
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Arthritis, Rheumatoid / diagnosis
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Arthritis, Rheumatoid / drug therapy
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Drug Eruptions / diagnosis*
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Drug Eruptions / physiopathology
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Female
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Follow-Up Studies
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Humans
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Infliximab
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Male
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Middle Aged
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Psoriasis / chemically induced*
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Psoriasis / physiopathology
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Risk Assessment
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Severity of Illness Index
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Spondylitis, Ankylosing / diagnosis
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Spondylitis, Ankylosing / drug therapy
Substances
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Antibodies, Monoclonal
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Antirheumatic Agents
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Infliximab