Fulminant hepatitis in an asymptomatic chronic carrier of hepatitis B virus mutant after withdrawal of low-dose methotrexate therapy for rheumatoid arthritis

MeSH terms

• Aged
• Arthritis, Rheumatoid / drug therapy*
• Arthritis, Rheumatoid / immunology
• Carrier State* / virology
• DNA, Viral / analysis
• Dose-Response Relationship, Drug
• Female
• Genetic Variation
• Hepatitis B / etiology*
• Hepatitis B / pathology
• Hepatitis B virus / genetics
• Humans
• Immunocompromised Host
• Immunosuppressive Agents / adverse effects*
• Methotrexate / adverse effects*
• Mutation