Prevalence and relation to risk factors of carotid atherosclerosis and left ventricular hypertrophy in systemic lupus erythematosus and antiphospholipid antibody syndrome

Am J Cardiol. 2001 Mar 1;87(5):663-6, A11. doi: 10.1016/s0002-9149(00)01453-3.

Abstract

The prevalence of preclinical cardiovascular disease was determined in women with systemic lupus erythematosus (SLE) and control subjects matched for traditional risk factors. Compared with control subjects, patients with SLE had a higher prevalence of carotid atherosclerosis (41% vs 9%, p < 0.005) and left ventricular hypertrophy (32% vs 5%, p < 0.005), supporting the possibility that chronic inflammation predisposes to premature cardiovascular disease in SLE.

MeSH terms

  • Adult
  • Antiphospholipid Syndrome / diagnosis*
  • Antiphospholipid Syndrome / epidemiology
  • Arteriosclerosis / diagnosis*
  • Arteriosclerosis / epidemiology
  • Carotid Stenosis / diagnosis*
  • Carotid Stenosis / epidemiology
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypertrophy, Left Ventricular / diagnosis*
  • Hypertrophy, Left Ventricular / epidemiology
  • Lupus Erythematosus, Systemic / diagnosis*
  • Lupus Erythematosus, Systemic / epidemiology
  • Middle Aged
  • Ontario
  • Pilot Projects
  • Risk