The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

B Conne; A Stutz; J D Vassalli

doi:10.1038/76211

The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

Nat Med. 2000 Jun;6(6):637-41. doi: 10.1038/76211.

Authors

B Conne¹, A Stutz, J D Vassalli

Affiliation

¹ Department of MorphologyFaculty of Medicine University of Geneva CMU, 1211 Geneva 4, Switzerland. beatrice.conn@medecine.unige.ch

PMID: 10835679
DOI: 10.1038/76211

Abstract

The role of the 3' untranslated region in posttranscriptional regulation of mRNA expression is being elucidated. Here we describe diseases arising from anomalies in this region, that affect the expression of one or more genes.

Publication types

Review

MeSH terms

3' Untranslated Regions / physiology*
Animals
Humans
Myotonic Dystrophy / genetics
Protein Biosynthesis
RNA Processing, Post-Transcriptional*
RNA Stability

Substances

3' Untranslated Regions