Using Multiple Anchor- and Distribution-Based Estimates to Evaluate Clinically Meaningful Change on the Functional Assessment of Cancer Therapy-Biologic Response Modifiers (FACT-BRM) Instrument
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Keywords
clinical significance
clinical trials
health-related quality of life
minimally important difference.
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Portions of this article were presented at the Assessing Clinical Significance for Quality of Life Measures in Oncology Research: State-of-the-Science Quality of Life Symposium, Rochester, MN, April 2002, and at the Drug Information Association 9th Annual Symposium for Quality of Life Evaluation, Hilton Head Island, SC, USA, March 2002.
Copyright © 2005 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.