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Wnt acylation

Seeing is believing

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A highly original and sensitive method using clickable bioorthogonal fatty acids and in situ proximity ligation enables the visualization of the palmitoylation of not only Wnt but also its fatty acyltransferase Porcupine in cells.

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Figure 1: Selective imaging of Wnt palmitoylation leads to a proposed model for Wnt3a processing and trafficking.

Katie Vicari

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  • 27 November 2013

    In the version of this article initially published online, the year in the publication date for reference 3 was listed as 2014 instead of 2013. The error has been corrected for the print, PDF and HTML versions of this article.

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Correspondence to Luc G Berthiaume.

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Berthiaume, L. Seeing is believing. Nat Chem Biol 10, 5–7 (2014). https://doi.org/10.1038/nchembio.1414

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