ReportDemographic and clinical properties of juvenile-onset Behçet's disease: A controlled multicenter study
Section snippets
Methods
Records of patients with BD from 9 medical centers in Turkey (Akdeniz, Baskent, Cukurova, Erciyes, Firat, Gazi, Inonu, Mersin, and Uludag Universities) were involved in this study.
A registration form and a detailed study questionnaire was prepared in the core center (Inonu University Medical Faculty Hospital, Malatya, Turkey) and sent to the satellite study centers. Medical records of all patients with juvenile- and adult-onset BD who were suitable to be included were cited into these forms and
Results
A total of 83 patients with juvenile-onset BD (38 male and 45 female) with a mean age of 19.6 ± 7.6 years (between 5 and 46 years) and 536 patients with adult-onset BD (293 male and 243 female) with a mean age of 39.2 ± 10.1 years (between 19 and 75 years) were enrolled. Mean age at the time of onset was 12.3 ± 3.5 years (between 1.1 and 16.0 years) in juvenile-onset BD and 31.7 ± 8.7 years (between 17.1 and 71.1 years) in patients with adult-onset BD. Family history was positive in 19% of
Discussion
Since the first article on pediatric BD by Mundy and Miller,14 several case reports and case studies have been published on this issue. Some of these publications stress that family history is more prominent, diagnosis is delayed, and disease course is more severe in pediatric patients with BD than adult counterparts, whereas other publications claim that no difference in these parameters exists.7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 There is little literature comparing adult- with
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Funding sources: None.
Conflicts of interest: None declared.
Presented as free communication at the XII International Conference on Behçet's Disease, in Lisbon, Portugal, on September 20-23, 2006.