Oral Surgery, Oral Medicine, Oral Pathology
Immunohistochemistry and ultrastructure of myoepithelium and modified myoepithelium of the ducts of human major salivary glands: Histogenetic implications for salivary gland tumors
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Basal cell adenoma with S-100 positive stroma: A case report and literature review
2016, Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyCitation Excerpt :BCA, first described by Kleinasser and Klein in 1967,11 is a rare benign salivary gland tumor, predominantly composed of basaloid cells, sharply demarcated by the stroma. Formerly considered a proliferation of a single epithelial type having some relationship with the basal cells of the salivary ducts, ultrastructural and immunohistochemical investigations have shown that this tumor is composed of a variable admixture of basal, ductal, and myoepithelial cells.1-3,12-15 Recently, it has been proposed that this tumor could form part of a continuum of benign salivary gland tumors, also including pleomorphic adenoma and myoepithelioma.3
Malignant salivary gland tumors and cyclo-oxygenase-2: A histopathological and immunohistochemical analysis with implications on histogenesis
2009, Oral OncologyCitation Excerpt :In our study, all cases of AdCC were negative for cox-2 expression whereas only two cases (20%) of PLGA showed strong cox-2 expression concomitant with the luminal cells of the duct-like structure, yet negative in the abluminal (myoepithelial) cells (Fig. 3c). Our results support the findings of previous studies that claim that the antigenic profile of PLGA and AdCC is consistent with its proposed derivation from the intercalated duct region29,32, yet differs from Dardick et al. which states that AdCC may arise from any level of the interlobular/intralobular duct system, not just the intercalated duct.26 In addition, our results support previous findings that found negative cox-2 overexpression in the myoepithelial cells of salivary gland tumors.33
Immunocytochemistry of myoepithelial cells in the salivary glands
2003, Progress in Histochemistry and CytochemistryBenign oncocytoma of the deep lobe of the parotid gland
1999, Journal of Oral and Maxillofacial SurgeryMaintenance of adult stem cells from human minor salivary glands via the Wnt signaling pathway
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This study was funded by a grant from the Moe Levin Family Foundation, Montreal, Quebec, Canada. We appreciate the manuscript preparation by Marilyn McDougall and the technical assistance in fluorescent microscopy by Judy Little.