Abstract
The evidence supporting a causal relationship between antiphospholipid (aPL) antibodies and cognitive dysfunction is very limited despite a general impression that one exists. Patients with aPL antibodies may complain of cognitive difficulties in their everyday lives, forcing the clinician to examine this issue. As with other non-thrombotic antiphospholipid syndrome (APS) manifestations, cognitive dysfunction in this population should be approached as a diagnosis of exclusion. The complexity in diagnosing and treating various manifestations of rheumatic disease holds true for identifying and addressing cognitive decline in these patients.
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Harrison, M.J., Ravdin, L.D. Cognitive dysfunction in the patient with antiphospholipid antibodies: Considerations for cause and treatment. Curr Rheumatol Rep 8, 89–94 (2006). https://doi.org/10.1007/s11926-006-0047-x
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DOI: https://doi.org/10.1007/s11926-006-0047-x