Abstract
The aim of this study was to assess spinal mobility status and Quality of life (QoL) of patients with ankylosing spondylitis (AS) and determine the relationship between spinal mobility and measures of clinical condition including QoL. A total of 74 patients with AS were included in this study. Disease specific instruments Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) were applied, and mobility testing: occiput-wall distance and chest expansion. QoL was assessed by the Short Form-36 (SF-36). The mean age was 48.5 years; there were significant correlations between BASMI score and age (P < 0.001), disease duration (P < 0.001), symptoms duration (P < 0.001) and BASFI (P < 0.001). BASMI was negatively correlated with SF-36 physical function subscale (P < 0.001) and general health subscale (P = 0.029). In multivariate regression analysis, BASFI score (P < 0.001) was independently associated factor with physical function domain of SF-36. This study showed that in AS spinal mobility measures are associated with physical function, general health, emotional role and mental health domains of QoL.
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References
Russell AS (1998) Ankylosing spondylitis—history. In: Klippel JH, Dieppe PA (eds) Rheumatology, 2nd edn. Mosby, London 1:14.1–2
Ward MM (1998) Quality of life in patients with ankylosing spondylitis. Rheum Dis Clin North Am 24:815–827. doi:10.1016/S0889-857X(05)70043-0
Van der Heijde D (2005) Function, mobility and quality of life in ankylosing spondylitis. Ann Rheum Dis 64(Suppl III):42
Jenkinson TR, Mallorie PA, Whitelock HC, Kennedy LG, Garrett SL, Calin A (1994) Defining spinal mobility in ankylosing spondylitis. The Bath Ankylosing Spondylitis Metrology Index (BASMI). J Rheumatol 21:1694–1698
Zochling J, Van der Heijde D, Burgos-Vargas R, Collantes E, Davis JC Jr, Dijkmans B, Dougados M, Géher P, Inman RD, Khan MA, Kvien TK, Leirisalo-Repo M, Olivieri I, Pavelka K, Sieper J, Stucki G, Sturrock RD, van der Linden S, Wendling D, Böhm H, van Royen BJ, Braun J (2006) ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 65:442–452. doi:10.1136/ard.2005.041137
Martindale J, Smith J, Sutton CJ, Greenan D, Goodacre L, Goodacre JA (2006) Disease and psychological status in ankylosing spondylitis. Rheumatology 45(10):1288–1293. doi:10.1093/rheumatology/kel115
Bostan EE, Borman P, Bodur H, Barça N (2003) Functional disability and quality of life in patients with ankylosing spondylitis. Rheumatol Int 23:121–126
Medical Outcomes Trust (ed) (1994) How to score the SF-36 Health Survey (SF-36). Medical Outcomes Trust, Boston
Gyatt GH, Feeney DH, Patric DL (1993) Measuring health-related quality of life. Ann Intern Med 118:622–629
Brazier JE, Harper R, Jones NM, O’Cathain A, Thomas KJ, Usherwood T, Westlake L (1992) Validating the SF 36 health survey questionnaire: new outcome measure for primary care. BMJ 305:160–164
Husted JA, Gladman DD, Farewell VT, Long JA, Cook RJ (1997) Validating the SF-36 Health Survey Questionnaire in patients with psoriatic arthritis. J Rheumatol 24(3):511–517
Ware JE Jr (2000) Using generic measures of functional health and well-being to increase understanding of disease burden. Spine 25:1467. doi:10.1097/00007632-200006150-00002
Turan Y, Duruöz MT, Cerrahogly L (2007) Quality of life in patients with ankylosing spondylitis: a pilot study. Rheumatol Int 27:895–899. doi:10.1007/s00296-007-0315-8
Turan Y, Duruöz MT, Bal S, Guvenc A, Cerrahogly L, Gurgan A (2007) Assessment of fatigue in patients with ankylosing spondylitis. Rheumatol Int 27:847–852. doi:10.1007/s00296-007-0313-x
Ariza-Ariza R, Hernandez-Cruz B, Navarro-Sarabia F (2003) Physical function and health-related quality of life of Spanish patients with ankylosing spondylitis. Arthritis Care Res 49(4):483–487. doi:10.1002/art.11197
Van Der Linden S, Valkenburg HA, Cats A (1984) Evaluation of diagnostic criteria for ankylosing spondylitis: a proposal for modification of the New York criteria. Arthritis Rheum 27:361–368. doi:10.1002/art.1780270401
Calin A, Garrett SL, Whitelock HC, Kennedy LG, O’Hea J, Mallorie P, Jenkinson T (1994) A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index (BASFI). J Rheumatol 21:2281–2285
Ruof J, Sangha O, Stucki G (1999) Comparative responsiveness of 3 functional indices in ankylosing spondylitis. J Rheumatol 26(9):1959–1963
Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A (1994) A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). J Rheumatol 21:2286–2291
Forejtová Š, Mann H, Štolfa J, Vedral K, Fenclová I, Némethová D, Pavelka K (2008) Factors influencing health status and disability of patients with ankylosing spondylitis in the Czech Republic. Clin Rheumatol 26:953–957
Mau W, Zeidler H, Mau R, Majewski A, Freyschmidt J, Stangel W, Deicher H (1998) Clinical features and prognosis of patients with possible ankylosing spondylitis. Results of 10-year follow-up. J Rheumatol 15:1109–1114
Feldtkeller E, Khan MA, van der Heijde D, van der Linden S, Braun J (2003) Age at disease onset and diagnosis delay in HLA-B27 negative vs. positive patients with ankylosing spondylitis. Rheumatol Int 23:61–66
Dagfinrud H, Mengshoel AM, Hagen KB, Loge JH, Kvien TK (2004) Health status of patients with ankylosing spondylitis: a comparison with the general population. Ann Rheum Dis 63:1605–1610. doi:10.1136/ard.2003.019224
Ward MM (1999) Health-related quality of life in ankylosing spondylitis: a survey of 175 patients. Arthritis Care Res 12(4):247–255. doi:10.1002/1529-0131(199908)12:4<247::AID-ART3>3.0.CO;2-H
Hamdi W, Azzouz D, Saadellaoui K, Daoud L, Kochbati S, Ben Hamida A, Zouari B, Kochir MM (2007) Correlations between Bath ankylosing spondylitis metrology index (BASMI), functional, structural, enthesopathy, disease activity index, and quality of life in 120 patients with ankylosing spondylitis. Ann Rheum Dis 66(Suppl II):398 abstract
Yakut E, Vardar Yagli N, Akdogan A, Kalyoncu U, Kiraz S, Çalgüneri M, Yakut Y, Ertenli I, Apras S (2006) Effects of Bath Ankylosing Spondylitis Metrology Index (BASMI) on Quality of Life in patients with ankylosing spondylitis. Ann Rheum Dis 65(Suppl II):676 abstract
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Vesović-Potić, V., Mustur, D., Stanisavljević, D. et al. Relationship between spinal mobility measures and quality of life in patients with ankylosing spondylitis. Rheumatol Int 29, 879–884 (2009). https://doi.org/10.1007/s00296-008-0759-5
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DOI: https://doi.org/10.1007/s00296-008-0759-5