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Cyclosporine-related reversible posterior leukoencephalopathy: MRI

  • DIAGNOSTIC NEURORADIOLOGY
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Abstract

Three patients aged 48, 11 and 40 years, two of whom were recent recipients of renal transplants and one of a bone marrow transplant, developed seizures, with cortical blindness in two cases. All were immunosuppressed with cyclosporine and were hypertensive at the onset of symptoms. MRI showed predominantly posterior signal changes in all three cases. The abnormalities were more conspicuous on fast FLAIR images than on conventional T2-weighted spin-echo images.

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Authors and Affiliations

  1. Dept. of Neuroimaging, King's College Hospital, Denmark Hill, London SE5, UK, , , , , , DK

    J. M. Jarosz

  2. Magnetic Resonance Centre, U. M. D. S. and Guy's and St. Thomas' Hospitals N. H. S. Trust, St. Thomas Street, London SE1 9RT, UK, , , , , , GB

    D. C. Howlett, T. C. S. Cox & J. B. Bingham

Authors
  1. J. M. Jarosz
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  2. D. C. Howlett
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  3. T. C. S. Cox
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  4. J. B. Bingham
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Received: 13 December 1996 Accepted: 22 January 1997

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Jarosz, J., Howlett, D., Cox, T. et al. Cyclosporine-related reversible posterior leukoencephalopathy: MRI. Neuroradiology 39, 711–715 (1997). https://doi.org/10.1007/s002340050492

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  • DOI: https://doi.org/10.1007/s002340050492

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