Skip to main content
SpringerLink
Log in

Clostridium difficile toxin-induced reactive arthritis in a patient with chronic Reiter's syndrome

  • Notes
  • Published:
European Journal of Clinical Microbiology and Infectious Diseases Aims and scope Submit manuscript

Abstract

The first case ofClostridium difficile toxin-induced reactive arthritis in a patient with chronic Reiter's syndrome is described and compared with previous cases of reactive arthritis associated with this organism. This case demonstrates how distinct clinical manifestations may develop at different times in Reiter's syndrome, according to the infecting organism. Diagnostic terminology is discussed in this context.Clostridium difficile should now be considered a firmly established cause of reactive arthritis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Fairweather SD, George RH, Keighley MRB Arthritis in pseudomembranous colitis associated with an antibody toClostridium difficile toxin. Journal of the Royal Society of Medicine 1980, 73: 524–525.

    PubMed  Google Scholar 

  2. Berglof FE Arthritis and intestinal infection. Acta Rheumatologica Scandinavica 1963, 9: 141–149.

    Google Scholar 

  3. Paronen I Reiter's disease: a study of 344 cases observed in Finland. Acta Rheumatologica Scandinavica 1948, Supplement 212: 1–114.

    Google Scholar 

  4. Ahronen P, Sievers K, Aho K Arthritis associated withYersinia enterocolitica infection. Acta Rheumatologica Scandinavica 1969, 15: 232–253.

    PubMed  Google Scholar 

  5. Urman JD, Zurier RB, Rothfield NF Reiter's syndrome associated withCampylobacter foetus infection. Annals of Internal Medicine 1977, 86: 444–445.

    PubMed  Google Scholar 

  6. Rollins RE, Moeller D Acute migratory polyarthritis associated with antibiotic-induced pseudomembranous colitis. American Journal of Gastroenterology 1976, 65: 353–355.

    PubMed  Google Scholar 

  7. Hannonen P, Hakola M, Mottonen T, Oka M Reactive oligoarthritis associated withClostridium difficile colitis. Scandinavian Journal of Rheumatology 1989, 18: 57–60.

    PubMed  Google Scholar 

  8. Brewerton DA HLA-B27 and the inheritance of susceptibility to rheumatic disease. Arthritis and Rheumatism 1976, 19: 656–668.

    PubMed  Google Scholar 

  9. Stein HB, Abdullah A, Robinson HS Salmonella reactive arthritis in British Columbia. Arthritis and Rheumatism 1980, 23: 206–210.

    PubMed  Google Scholar 

  10. Leung FY-K, Littlejohn GO, Bombardier C Reiter's syndrome afterCampylobacter jejuni enteritis. Arthritis and Rheumatism 1980, 23: 948–950.

    PubMed  Google Scholar 

  11. Marsal L, Winblad S, Wollheim FA Yersinia enterocolitica arthritis in southern Sweden; a four-year follow-up study. British Medical Journal 1981, 283: 101–103.

    PubMed  Google Scholar 

  12. Keat A Reiter's syndrome and reactive arthritis in perspective. New England Journal of Medicine 1983, 309: 1606–1614.

    PubMed  Google Scholar 

  13. Aho K Yersinia arthritis and related diseases: clinical and immunogenetic implications. In: Dumonde DC (ed): Infection and immunology in the rheumatic diseases. Blackwell Scientific, Oxford, 1976, p. 341–344.

    Google Scholar 

  14. Rothschild BM, Masi AT, June PL Arthritis associated with ampicillin colitis. Archives of Internal Medicine 1977, 137: 1605–1607.

    PubMed  Google Scholar 

  15. Hodgson HJ, Potter JF, Jewell DP Immune complexes in ulcerative colitis and Crohn's disease. Clinical and Experimental Immunology 1977, 29: 187–196.

    PubMed  Google Scholar 

  16. Gemmel CG Comparative study of the nature and biological activities of bacterial endotoxins. Journal of Medical Microbiology 1984, 17: 217–235.

    PubMed  Google Scholar 

  17. Chang Te-Wen: Antibiotic-associated injury to the gut. In: Berg JE (ed): Bockus gastroenterology. W.B. Saunders, 1985, p. 2583–2592.

  18. Smith MD, Gibson RA, Brooks PR Abnormal bowel permeability in ankylosing spondylitis and rheumatoid arthritis. Journal of Rheumatology 1985, 12: 299–305.

    PubMed  Google Scholar 

  19. Bolton RP, Wood GM, Losowsky MS Acute arthritis associated withClostridium difficile colitis. British Medical Journal 1981, 283: 1023–1024.

    PubMed  Google Scholar 

  20. McCluskey J, Riley TV, Owen ET, Langlands DR Reactive arthritis associated withClostridium difficile. Australian and New Zealand Journal of Medicine 1982, 12: 535–537.

    PubMed  Google Scholar 

  21. Lofgren RP, Tadlock LM, Soltis RD Acute oligoarthritis associated withClostridium difficile pseudomembranous colitis. Archives of Internal Medicine 1984, 144: 617–619.

    PubMed  Google Scholar 

  22. Abbott WG, Cauchey DE Reactive arthritis due toClostridium difficile. New Zealand Medical Journal 1982, 95: 287.

    Google Scholar 

  23. Atkinson MH, McLeod BD Reactive arthritis associated withClostridium difficile enteritis. Journal of Rheumatology 1988, 15: 520–522.

    PubMed  Google Scholar 

  24. Mermel LA, Osborn TG Clostridium difficile associated reactive arthritis in an HLA-B27 positive female: report and literature review. Journal of Rheumatology 1988, 16: 133–135.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Rheumatology, Charing Cross Hospital, Fulham, London W6, UK

    A. Cope

  2. Department of Genital Medicine, St. Bartholomew's Hospital, West Smithfield, EC1A 7BE, London, UK

    J. Anderson

  3. Department of Infectious Diseases, The Lister Unit, Northwick Park Hospital, Watford Road, HA1 3UJ, Harrow, Middlesex, UK

    E. Wilkins

Authors
  1. A. Cope
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Anderson
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Wilkins
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cope, A., Anderson, J. & Wilkins, E. Clostridium difficile toxin-induced reactive arthritis in a patient with chronic Reiter's syndrome. Eur. J. Clin. Microbiol. Infect. Dis. 11, 40–43 (1992). https://doi.org/10.1007/BF01971269

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01971269

Keywords

Search

Navigation