Summary
The authors report a case of allergic granulomatous vasculitis with prominent intestinal symptoms (abdominal pain, bloody diarrhea) due to a widespread involvement of the gut and associated with the presence of a monoclonal IgG in the serum (without evidence of myeloma). Rectoscopy showed nonspecific proctitis, but both pathological hallmarks of the disease (allergic vasculitis and extravascular tuberculoid granulomas) were present on reactal biopsy specimens. At laparotomy, vasculitis nodules were scattered throughout the visceral serosa, omentum, and gastrocolic ligament. Histology of omental nodules revealed the full-blown picture of allergic granulomatous angiitis. Steroids induced a dramatic and prolonged improvement of the digestive symptoms.
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Modigliani, R., Muschart, JM., Galian, A. et al. Allergic granulomatous vasculitis (Churg-Strauss syndrome). Digest Dis Sci 26, 264–270 (1981). https://doi.org/10.1007/BF01391641
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DOI: https://doi.org/10.1007/BF01391641