Regular articleRelationships between clinical parameters, interleukin 1B and histopathologic findings of gingival tissue in periodontitis patients
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Sulfated polysaccharides from the marine algae Gracilaria caudata prevent tissue damage caused by ligature-induced periodontitis
2019, International Journal of Biological MacromoleculesCitation Excerpt :Within several cytokines that are observed during periodontitis is the interleukin-1B. A high level of this mediator is according to high GBI score and PPD value [28]. The PLS from G. caudata was shown to reduce interleukin-1B levels during induced inflammation [10].
Serum interleukin-1β in subjects with abdominal obesity and periodontitis
2015, Obesity Research and Clinical PracticeCitation Excerpt :An inflamed periodontium is a potential reservoir of endotoxins and cytokines [26]. The findings of this study supplement earlier information on cytokine synthesis in response to periodontopathogenic bacteria and their products [27]. Evidence suggested that both keratinocytes and gingival fibroblasts produce interleukin-1β in response to stimulation by bacterial products [28].
Integrin α5β1 Activates the NLRP3 Inflammasome by Direct Interaction with a Bacterial Surface Protein
2012, ImmunityCitation Excerpt :Periodontitis, one of the most prevalent oral diseases, is a chronic inflammatory disease and major cause of tooth loss induced by bacteria in the subgingival sulcus and is progressed by host factors that are exaggerated by inflammation and immune reactions. The proinflammatory and bone-resorptive characteristics of IL-1β are associated with the immunopathology of periodontitis, leading to periodontal tissue destruction (Liu et al., 1996). IL-1β is increased in the gingival crevicular fluid of periodontitis patients and correlates to the presence of major periodontopathogens, such as Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola, the so-called red complex (Teles et al., 2010), and to disease severity (Ferreira et al., 2008).
Structural and functional comparison of cytokine interleukin-1 beta from chicken and human
2011, Molecular ImmunologyCitation Excerpt :The active IL-1β is then able to interact with type I interleukin-1 receptor (IL-1R type I) and induce the expression of immune-related molecules such as cytokines and chemokines, thus triggering a cascade of immune responses (Dinarello, 1996; Introna et al., 1993). IL-1β dysfunction is associated with tumorigenesis, cardiovascular disease, rheumatoid arthritis, and periodontal disease (Liu et al., 1996; Stern et al., 2003; Vidal-Vanaclocha et al., 2000). In contrast to mammalian IL-1βs, little is known about the characteristics of avian IL-1βs.
Predictive periodontitis: The most promising salivary biomarkers for early diagnosis of periodontitis
2021, Journal of Clinical Medicine