T-Lymphocyte subsets

Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis
Alyxzandria M Gaydosik, Tracy Tabib, Robyn Domsic, Dinesh Khanna, Robert Lafyatis, Patrizia Fuschiotti

Annals of the Rheumatic Diseases Nov 2021, 80 (11) 1453-1460; DOI: 10.1136/annrheumdis-2021-220209
Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis
Achilleas Floudas, Nuno Neto, Carl Orr, Mary Canavan, Phil Gallagher, Conor Hurson, Michael G Monaghan, Sunil Nagpar, Ronan H Mullan, Douglas J Veale, Ursula Fearon

Annals of the Rheumatic Diseases Oct 2021, annrheumdis-2021-220458; DOI: 10.1136/annrheumdis-2021-220458
Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis
Ignatius Ryan Adriawan, Faranaz Atschekzei, Oliver Dittrich-Breiholz, Panagiotis Garantziotis, Stefanie Hirsch, Linus Maximillian Risser, Maike Kosanke, Reinhold Ernst Schmidt, Torsten Witte, Georgios Sogkas

Annals of the Rheumatic Diseases Sep 2021, annrheumdis-2021-220955; DOI: 10.1136/annrheumdis-2021-220955
Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages
Linyu Geng, Jian Zhao, Yun Deng, Ivan Molano, Xue Xu, Lingxiao Xu, Phillip Ruiz, Quanzhen Li, Xuebing Feng, Miaojia Zhang, Wenfeng Tan, Diane L Kamen, Sang-Cheol Bae, Gary S Gilkeson, Lingyun Sun, Betty P Tsao

Annals of the Rheumatic Diseases Sep 2021, annrheumdis-2021-220793; DOI: 10.1136/annrheumdis-2021-220793
Immune response to dermatomyositis-specific autoantigen, transcriptional intermediary factor 1γ can result in experimental myositis
Naoko Okiyama, Yuki Ichimura, Miwako Shobo, Ryota Tanaka, Noriko Kubota, Akimasa Saito, Yosuke Ishitsuka, Rei Watanabe, Yasuhiro Fujisawa, Yoshiyuki Nakamura, Akihiro Murakami, Hisako Kayama, Kiyoshi Takeda, Manabu Fujimoto

Annals of the Rheumatic Diseases Sep 2021, 80 (9) 1201-1208; DOI: 10.1136/annrheumdis-2020-218661
Novel self-amplificatory loop between T cells and tenocytes as a driver of chronicity in tendon disease
Emma Garcia-Melchor, Giacomo Cafaro, Lucy MacDonald, Lindsay A N Crowe, Shatakshi Sood, Michael McLean, Umberto G Fazzi, Iain B McInnes, Moeed Akbar, Neal L Millar

Annals of the Rheumatic Diseases Aug 2021, 80 (8) 1075-1085; DOI: 10.1136/annrheumdis-2020-219335
B cell depletion impairs vaccination-induced CD8⁺ T cell responses in a type I interferon-dependent manner
Theresa Graalmann, Katharina Borst, Himanshu Manchanda, Lea Vaas, Matthias Bruhn, Lukas Graalmann, Mario Koster, Murielle Verboom, Michael Hallensleben, Carlos Alberto Guzmán, Gerd Sutter, Reinhold E Schmidt, Torsten Witte, Ulrich Kalinke

Annals of the Rheumatic Diseases Jul 2021, annrheumdis-2021-220435; DOI: 10.1136/annrheumdis-2021-220435
Systematic evaluation of nine monogenic autoinflammatory diseases reveals common and disease-specific correlations with allergy-associated features
Daniella Muallem Schwartz, Moses M Kitakule, Brian LP Dizon, Cristhian Gutierrez-Huerta, Sarah A Blackstone, Aarohan M Burma, Aran Son, Natalie Deuitch, Sofia Rosenzweig, Hirsh Komarow, Deborah L Stone, Anne Jones, Michele Nehrebecky, Patrycja Hoffmann, Tina Romeo, Adriana Almeida de Jesus, Sara Alehashemi, Megha Garg, Sofia Torreggiani, Gina A Montealegre Sanchez, Katelin Honer, Gema Souto Adeva, Karyl S Barron, Ivona Aksentijevich, Amanda K Ombrello, Raphaela Goldbach-Mansky, Daniel L Kastner, Joshua D Milner, Pamela Frischmeyer-Guerrerio

Annals of the Rheumatic Diseases Jun 2021, 80 (6) 788-795; DOI: 10.1136/annrheumdis-2020-219137
Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma
Elena Pontarini, William James Murray-Brown, Cristina Croia, Davide Lucchesi, James Conway, Felice Rivellese, Liliane Fossati-Jimack, Elisa Astorri, Edoardo Prediletto, Elisa Corsiero, Francesca Romana Delvecchio, Rachel Coleby, Eva Gelbhardt, Aurora Bono, Chiara Baldini, Ilaria Puxeddu, Piero Ruscitti, Roberto Giacomelli, Francesca Barone, Benjamin Fisher, Simon J Bowman, Serena Colafrancesco, Roberta Priori, Nurhan Sutcliffe, Stephen Challacombe, Gianluca Carlesso, Anwar Tappuni, Costantino Pitzalis, Michele Bombardieri

Annals of the Rheumatic Diseases Dec 2020, 79 (12) 1588-1599; DOI: 10.1136/annrheumdis-2020-217646
Response to: ‘Correspondence to ‘Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression’’ by Wang and Ma
Abdulla Watad, Charlie Bridgewood, Dennis G McGonagle

Annals of the Rheumatic Diseases Oct 2020, annrheumdis-2020-219047; DOI: 10.1136/annrheumdis-2020-219047

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