T Cells

T cell subsets: an immunological biomarker to predict progression to clinical arthritis in ACPA-positive individuals
L Hunt, E M Hensor, J Nam, A N Burska, R Parmar, P Emery, F Ponchel

Annals of the Rheumatic Diseases Oct 2016, 75 (10) 1884-1889; DOI: 10.1136/annrheumdis-2015-207991
Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis
Gudrun Reynisdottir, Helga Olsen, Vijay Joshua, Marianne Engström, Helena Forsslund, Reza Karimi, C Magnus Sköld, Sven Nyren, Anders Eklund, Johan Grunewald, Anca I Catrina

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1722-1727; DOI: 10.1136/annrheumdis-2015-208216
Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes
Dag Leonard, Maija-Leena Eloranta, Niklas Hagberg, Olof Berggren, Karolina Tandre, Gunnar Alm, Lars Rönnblom

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1728-1734; DOI: 10.1136/annrheumdis-2015-208055
The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression
Matteo Vecellio, Amity R Roberts, Carla J Cohen, Adrian Cortes, Julian C Knight, Paul Bowness, B Paul Wordsworth

Annals of the Rheumatic Diseases Aug 2016, 75 (8) 1534-1540; DOI: 10.1136/annrheumdis-2015-207490
Efficacy of abatacept for IgG4-related disease over 8 months
Motohisa Yamamoto, Hiroki Takahashi, Kenichi Takano, Yui Shimizu, Nodoka Sakurai, Chisako Suzuki, Yasuyoshi Naishiro, Hidetaka Yajima, Teruhito Awakawa, Tetsuo Himi, Hiroshi Nakase

Annals of the Rheumatic Diseases Aug 2016, 75 (8) 1576-1578; DOI: 10.1136/annrheumdis-2016-209368
Response to: ‘Issues with anti-Gr1 antibody-mediated myeloid-derived suppressor cell depletion’ by Xing et al
Xiang-Yang Wang, Huanfa Yi, Juan Li

Annals of the Rheumatic Diseases Aug 2016, 75 (8) e50; DOI: 10.1136/annrheumdis-2016-209848
Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus
Caroline von Spee-Mayer, Elise Siegert, Dimas Abdirama, Angelika Rose, Anika Klaus, Tobias Alexander, Philipp Enghard, Birgit Sawitzki, Falk Hiepe, Andreas Radbruch, Gerd-Rüdiger Burmester, Gabriela Riemekasten, Jens Y Humrich

Annals of the Rheumatic Diseases Jul 2016, 75 (7) 1407-1415; DOI: 10.1136/annrheumdis-2015-207776
RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation
Lynett Danks, Noriko Komatsu, Matteo M Guerrini, Shinichiro Sawa, Marietta Armaka, George Kollias, Tomoki Nakashima, Hiroshi Takayanagi

Annals of the Rheumatic Diseases Jun 2016, 75 (6) 1187-1195; DOI: 10.1136/annrheumdis-2014-207137
Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis
G Reynolds, J R Gibbon, A G Pratt, M J Wood, D Coady, G Raftery, A R Lorenzi, A Gray, A Filer, C D Buckley, M A Haniffa, J D Isaacs, C M U Hilkens

Annals of the Rheumatic Diseases May 2016, 75 (5) 899-907; DOI: 10.1136/annrheumdis-2014-206578
Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis
Liye Chen, Anna Ridley, Ariane Hammitzsch, Mohammad Hussein Al-Mossawi, Helen Bunting, Dimitris Georgiadis, Antoni Chan, Simon Kollnberger, Paul Bowness

Annals of the Rheumatic Diseases May 2016, 75 (5) 916-923; DOI: 10.1136/annrheumdis-2014-206996

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