T Cells

IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis
Eric Gracey, Zoya Qaiyum, Ibrahim Almaghlouth, Daeria Lawson, Susan Karki, Naga Avvaru, Zhenbo Zhang, Yuchen Yao, Vidya Ranganathan, Yuriy Baglaenko, Robert D Inman

Annals of the Rheumatic Diseases Dec 2016, 75 (12) 2124-2132; DOI: 10.1136/annrheumdis-2015-208902
Treatment with abatacept prevents experimental dermal fibrosis and induces regression of established inflammation-driven fibrosis
Matthieu Ponsoye, Camelia Frantz, Nadira Ruzehaji, Carole Nicco, Muriel Elhai, Barbara Ruiz, Anne Cauvet, Sonia Pezet, Marie Laure Brandely, Frédéric Batteux, Yannick Allanore, Jérôme Avouac

Annals of the Rheumatic Diseases Dec 2016, 75 (12) 2142-2149; DOI: 10.1136/annrheumdis-2015-208213
An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation
Amity R Roberts, Matteo Vecellio, Liye Chen, Anna Ridley, Adrian Cortes, Julian C Knight, Paul Bowness, Carla J Cohen, B Paul Wordsworth

Annals of the Rheumatic Diseases Dec 2016, 75 (12) 2150-2156; DOI: 10.1136/annrheumdis-2015-208640
Nucleosome in patients with systemic sclerosis: possible association with immunological abnormalities via abnormal activation of T and B cells
Ayumi Yoshizaki, Takashi Taniguchi, Ryosuke Saigusa, Takemichi Fukasawa, Satoshi Ebata, Hiroko Numajiri, Kouki Nakamura, Takashi Yamashita, Takehiro Takahashi, Tetsuo Toyama, Yoshihide Asano, Thomas F Tedder, Shinichi Sato

Annals of the Rheumatic Diseases Oct 2016, 75 (10) 1858-1865; DOI: 10.1136/annrheumdis-2015-207405
T cell subsets: an immunological biomarker to predict progression to clinical arthritis in ACPA-positive individuals
L Hunt, E M Hensor, J Nam, A N Burska, R Parmar, P Emery, F Ponchel

Annals of the Rheumatic Diseases Oct 2016, 75 (10) 1884-1889; DOI: 10.1136/annrheumdis-2015-207991
Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis
Gudrun Reynisdottir, Helga Olsen, Vijay Joshua, Marianne Engström, Helena Forsslund, Reza Karimi, C Magnus Sköld, Sven Nyren, Anders Eklund, Johan Grunewald, Anca I Catrina

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1722-1727; DOI: 10.1136/annrheumdis-2015-208216
Activated T cells enhance interferon-α production by plasmacytoid dendritic cells stimulated with RNA-containing immune complexes
Dag Leonard, Maija-Leena Eloranta, Niklas Hagberg, Olof Berggren, Karolina Tandre, Gunnar Alm, Lars Rönnblom

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1728-1734; DOI: 10.1136/annrheumdis-2015-208055
The genetic association of RUNX3 with ankylosing spondylitis can be explained by allele-specific effects on IRF4 recruitment that alter gene expression
Matteo Vecellio, Amity R Roberts, Carla J Cohen, Adrian Cortes, Julian C Knight, Paul Bowness, B Paul Wordsworth

Annals of the Rheumatic Diseases Aug 2016, 75 (8) 1534-1540; DOI: 10.1136/annrheumdis-2015-207490
Efficacy of abatacept for IgG4-related disease over 8 months
Motohisa Yamamoto, Hiroki Takahashi, Kenichi Takano, Yui Shimizu, Nodoka Sakurai, Chisako Suzuki, Yasuyoshi Naishiro, Hidetaka Yajima, Teruhito Awakawa, Tetsuo Himi, Hiroshi Nakase

Annals of the Rheumatic Diseases Aug 2016, 75 (8) 1576-1578; DOI: 10.1136/annrheumdis-2016-209368
Response to: ‘Issues with anti-Gr1 antibody-mediated myeloid-derived suppressor cell depletion’ by Xing et al
Xiang-Yang Wang, Huanfa Yi, Juan Li

Annals of the Rheumatic Diseases Aug 2016, 75 (8) e50; DOI: 10.1136/annrheumdis-2016-209848

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