Circulating follicular helper T cells are increased in systemic sclerosis and promote plasmablast differentiation through the IL-21 pathway which can be inhibited by ruxolitinib
Laure Ricard, Vincent Jachiet, Florent Malard, Yishan Ye, Nicolas Stocker, Sébastien Rivière, Patricia Senet, Jean-Benoit Monfort, Olivier Fain, Mohamad Mohty, Béatrice Gaugler, Arsène Mekinian
Annals of the Rheumatic Diseases Apr 2019, 78 (4) 539-550; DOI: 10.1136/annrheumdis-2018-214382