Methotrexate

Methotrexate dosage as a source of bias in biological trials in rheumatoid arthritis: a systematic review
Josefina Durán, Margarita Bockorny, Deepan Dalal, Michael LaValley, David T Felson

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1595-1598; DOI: 10.1136/annrheumdis-2016-209383
Why methotrexate suboptimal dosing is a potential source of bias in biologic drugs clinical trials
Josefina Durán, David T Felson

Annals of the Rheumatic Diseases Aug 2016, 75 (8) e53; DOI: 10.1136/annrheumdis-2016-209791
Let's re-examine these MTX points once again
J M Kremer

Annals of the Rheumatic Diseases Aug 2016, 75 (8) e54; DOI: 10.1136/annrheumdis-2016-209834
A patient-initiated DMARD self-monitoring service for people with rheumatoid or psoriatic arthritis on methotrexate: a randomised controlled trial
Hayley McBain, Michael Shipley, Abigail Olaleye, Samantha Moore, Stanton Newman

Annals of the Rheumatic Diseases Jul 2016, 75 (7) 1343-1349; DOI: 10.1136/annrheumdis-2015-207768
The comparative effectiveness of oral versus subcutaneous methotrexate for the treatment of early rheumatoid arthritis
Glen S Hazlewood, J Carter Thorne, Janet E Pope, Daming Lin, Diane Tin, Gilles Boire, Boulos Haraoui, Carol A Hitchon, Edward C Keystone, Shahin Jamal, Vivian P Bykerk

Annals of the Rheumatic Diseases Jun 2016, 75 (6) 1003-1008; DOI: 10.1136/annrheumdis-2014-206504
Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques
Philip G Conaghan, Mikkel Østergaard, Michael A Bowes, Chunying Wu, Thomas Fuerst, Désirée van der Heijde, Fedra Irazoque-Palazuelos, Oscar Soto-Raices, Pawel Hrycaj, Zhiyong Xie, Richard Zhang, Bradley T Wyman, John D Bradley, Koshika Soma, Bethanie Wilkinson

Annals of the Rheumatic Diseases Jun 2016, 75 (6) 1024-1033; DOI: 10.1136/annrheumdis-2015-208267
Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial
Gerd R Burmester, William F Rigby, Ronald F van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ariella Kelman, Sophie Dimonaco, Nina Mitchell

Annals of the Rheumatic Diseases Jun 2016, 75 (6) 1081-1091; DOI: 10.1136/annrheumdis-2015-207628
Does a family history of RA influence the clinical presentation and treatment response in RA?
Thomas Frisell, Saedis Saevarsdottir, Johan Askling

Annals of the Rheumatic Diseases Jun 2016, 75 (6) 1120-1125; DOI: 10.1136/annrheumdis-2015-207670
Long-term safety of etanercept and adalimumab compared to methotrexate in patients with juvenile idiopathic arthritis (JIA)
Jens Klotsche, Martina Niewerth, Johannes-Peter Haas, Hans-Iko Huppertz, Angela Zink, Gerd Horneff, Kirsten Minden

Annals of the Rheumatic Diseases May 2016, 75 (5) 855-861; DOI: 10.1136/annrheumdis-annrheumdis-2014-206747
Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation
C C Thornton, F Al-Rashed, D Calay, G M Birdsey, A Bauer, H Mylroie, B J Morley, A M Randi, D O Haskard, J J Boyle, J C Mason

Annals of the Rheumatic Diseases Feb 2016, 75 (2) 439-448; DOI: 10.1136/annrheumdis-2014-206305

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