Knee Osteoarthritis

Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis
Neng-Yu Lin, Alfiya Distler, Christian Beyer, Ariella Philipi-Schöbinger, Silvia Breda, Clara Dees, Michael Stock, Michal Tomcik, Andreas Niemeier, Francesco Dell'Accio, Kolja Gelse, Mark P Mattson, Georg Schett, Jörg HW Distler

Annals of the Rheumatic Diseases Nov 2016, 75 (11) 2037-2044; DOI: 10.1136/annrheumdis-2015-208420
Differential roles of TGF-β signalling in joint tissues during osteoarthritis development
Ting Yu Wang, Di Chen

Annals of the Rheumatic Diseases Nov 2016, 75 (11) e72; DOI: 10.1136/annrheumdis-2016-210312
Painful knee but not hand osteoarthritis is an independent predictor of mortality over 23 years follow-up of a population-based cohort of middle-aged women
S Kluzek, M T Sanchez-Santos, K M Leyland, A Judge, T D Spector, D Hart, C Cooper, J Newton, N K Arden

Annals of the Rheumatic Diseases Oct 2016, 75 (10) 1749-1756; DOI: 10.1136/annrheumdis-2015-208056
Signal intensity alteration in the infrapatellar fat pad at baseline for the prediction of knee symptoms and structure in older adults: a cohort study
Weiyu Han, Dawn Aitken, Zhaohua Zhu, Andrew Halliday, Xia Wang, Benny Antony, Flavia Cicuttini, Graeme Jones, Changhai Ding

Annals of the Rheumatic Diseases Oct 2016, 75 (10) 1783-1788; DOI: 10.1136/annrheumdis-2015-208360
Osteoarthritic bone marrow lesions almost exclusively colocate with denuded cartilage: a 3D study using data from the Osteoarthritis Initiative
Michael A Bowes, Stewart WD McLure, Christopher BH Wolstenholme, Graham R Vincent, Sophie Williams, Andrew Grainger, Philip G Conaghan

Annals of the Rheumatic Diseases Oct 2016, 75 (10) 1852-1857; DOI: 10.1136/annrheumdis-2015-208407
Response to: ‘The role of infrapatellar fat pad resection in total knee arthroplasty’ by White et al
Weiyu Han, Faming Pan, Zhenhua Liu, Zhaohua Zhu, Xia Wang, Shuang Zheng, Benny Antony, Changhai Ding

Annals of the Rheumatic Diseases Oct 2016, 75 (10) e67; DOI: 10.1136/annrheumdis-2016-210170
Longitudinal validation of periarticular bone area and 3D shape as biomarkers for knee OA progression? Data from the FNIH OA Biomarkers Consortium
David Hunter, Michael Nevitt, John Lynch, Virginia Byers Kraus, Jeffrey N Katz, Jamie E Collins, Mike Bowes, Ali Guermazi, Frank W Roemer, Elena Losina

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1607-1614; DOI: 10.1136/annrheumdis-2015-207602
Clinical significance of worsening versus stable preradiographic MRI lesions in a cohort study of persons at higher risk for knee osteoarthritis
Leena Sharma, Michael Nevitt, Marc Hochberg, Ali Guermazi, Frank W Roemer, Michel Crema, Charles Eaton, Rebecca Jackson, Kent Kwoh, Jane Cauley, Orit Almagor, Joan S Chmiel

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1630-1636; DOI: 10.1136/annrheumdis-2015-208129
Low dose of fish oil in osteoarthritis: low effect?
X Chevalier, F Eymard

Annals of the Rheumatic Diseases Jul 2016, 75 (7) e41; DOI: 10.1136/annrheumdis-2016-209399
Can genetics explain the higher risk of worsening knee pain in offspring of people with total knee replacement for severe primary knee osteoarthritis?
Ting Zou, Li Yang, Ashley M Lee, Xia Tan, Elizabeth Wong, Harrison X Bai

Annals of the Rheumatic Diseases Jul 2016, 75 (7) e45; DOI: 10.1136/annrheumdis-2016-209380

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