Fibroblasts

Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages
Christiane Maier, Andreas Ramming, Christina Bergmann, Rita Weinkam, Nicolai Kittan, Georg Schett, Jörg H W Distler, Christian Beyer

Annals of the Rheumatic Diseases Jun 2017, 76 (6) 1133-1141; DOI: 10.1136/annrheumdis-2016-210189
IL-22 capacitates dermal fibroblast responses to TNF in scleroderma
Nicolò Costantino Brembilla, Aleksandra Maria Dufour, Montserrat Alvarez, Stéphanie Hugues, Elisa Montanari, Marie-Elise Truchetet, Paola Lonati, Lionel Fontao, Armando Gabrielli, Serena Vettori, Gabriele Valentini, Wolf-Henning Boehncke, Pierluigi Meroni, Carlo Chizzolini

Annals of the Rheumatic Diseases Sep 2016, 75 (9) 1697-1705; DOI: 10.1136/annrheumdis-2015-207477
Poly(ADP-ribose) polymerase-1 regulates fibroblast activation in systemic sclerosis
Yun Zhang, Sebastian Pötter, Chih-Wei Chen, Ruifang Liang, Kolja Gelse, Ingo Ludolph, Raymund E Horch, Oliver Distler, Georg Schett, Jörg H W Distler, Clara Dees

Annals of the Rheumatic Diseases May 2018, 77 (5) 744-751; DOI: 10.1136/annrheumdis-2017-212265
Identification of a transitional fibroblast function in very early rheumatoid arthritis
Andrew Filer, Lewis S C Ward, Samuel Kemble, Christopher S Davies, Hafsa Munir, Rebekah Rogers, Karim Raza, Christopher Dominic Buckley, Gerard B Nash, Helen M McGettrick

Annals of the Rheumatic Diseases Dec 2017, 76 (12) 2105-2112; DOI: 10.1136/annrheumdis-2017-211286
Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis
Mirko Manetti, Eloisa Romano, Irene Rosa, Serena Guiducci, Silvia Bellando-Randone, Amato De Paulis, Lidia Ibba-Manneschi, Marco Matucci-Cerinic

Annals of the Rheumatic Diseases May 2017, 76 (5) 924-934; DOI: 10.1136/annrheumdis-2016-210229
The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc
Ruifang Liang, Barbora Šumová, Cinzia Cordazzo, Tatjana Mallano, Yun Zhang, Thomas Wohlfahrt, Clara Dees, Andreas Ramming, Dorota Krasowska, Małgorzata Michalska-Jakubus, Oliver Distler, Georg Schett, Ladislav Šenolt, Jörg H W Distler

Annals of the Rheumatic Diseases Apr 2017, 76 (4) 756-764; DOI: 10.1136/annrheumdis-2016-209698
Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling
Chih-Wei Chen, Christian Beyer, Jun Liu, Christiane Maier, Chun Li, Thuong Trinh-Minh, Xiaohan Xu, Stuart H Cole, Mindy H Hsieh, Nicholas Ng, Alana Althage, Shelly Meeusen, Shifeng Pan, Eric C Svensson, H Martin Seidel, Georg Schett, Peter Gergely, Jennifer L Harris, Jörg H W Distler

Annals of the Rheumatic Diseases Apr 2017, 76 (4) 773-778; DOI: 10.1136/annrheumdis-2016-210294
JAK1-dependent transphosphorylation of JAK2 limits the antifibrotic effects of selective JAK2 inhibitors on long-term treatment
Yun Zhang, Ruifang Liang, Chih-Wei Chen, Tatjana Mallano, Clara Dees, Alfiya Distler, Adam Reich, Christina Bergmann, Andreas Ramming, Kolja Gelse, Dirk Mielenz, Oliver Distler, Georg Schett, Jörg H W Distler

Annals of the Rheumatic Diseases Aug 2017, 76 (8) 1467-1475; DOI: 10.1136/annrheumdis-2016-210911
Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis
Katrin Palumbo-Zerr, Alina Soare, Pawel Zerr, Andrea Liebl, Rossella Mancuso, Michal Tomcik, Barbora Sumova, Clara Dees, Chih-Wei Chen, Thomas Wohlfahrt, Tatjana Mallano, Alfiya Distler, Andreas Ramming, Kolja Gelse, Carina Mihai, Oliver Distler, Georg Schett, Jörg H W Distler

Annals of the Rheumatic Diseases Jan 2017, 76 (1) 244-251; DOI: 10.1136/annrheumdis-2015-208470
Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes
Chiara Angiolilli, Pawel A Kabala, Aleksander M Grabiec, Iris M Van Baarsen, Bradley S Ferguson, Samuel García, Beatriz Malvar Fernandez, Timothy A McKinsey, Paul P Tak, Gianluca Fossati, Paolo Mascagni, Dominique L Baeten, Kris A Reedquist

Annals of the Rheumatic Diseases Jan 2017, 76 (1) 277-285; DOI: 10.1136/annrheumdis-2015-209064

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