Fibroblasts

PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis
Yun Zhang, Lichong Shen, Honglin Zhu, Katja Dreissigacker, Diana Distler, Xiang Zhou, Andrea Hermina Györfi, Christina Bergmann, Xianyi Meng, Clara Dees, Thuong Trinh-Minh, Ingo Ludolph, Raymund Horch, Andreas Ramming, Georg Schett, Jörg H W Distler

Annals of the Rheumatic Diseases Sep 2020, 79 (9) 1227-1233; DOI: 10.1136/annrheumdis-2020-216963
Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging
Christian Schmidkonz, Simon Rauber, Armin Atzinger, Rahul Agarwal, Theresa Ida Götz, Alina Soare, Michael Cordes, Olaf Prante, Christina Bergmann, Arnd Kleyer, Philipp Ritt, Simone Maschauer, Peter Hennig, Johannes Toms, Markus Köhner, Bernhard Manger, John H Stone, Uwe Haberkorn, Tobias Baeuerle, Jörg H W Distler, Abbas Agaimy, Torsten Kuwert, Georg Schett, Andreas Ramming

Annals of the Rheumatic Diseases Jul 2020, annrheumdis-2020-217408; DOI: 10.1136/annrheumdis-2020-217408
Could autologous adipose-derived stromal vascular fraction turn out an unwanted source of profibrotic myofibroblasts in systemic sclerosis?
Mirko Manetti

Annals of the Rheumatic Diseases May 2020, 79 (5) e55; DOI: 10.1136/annrheumdis-2019-215288
Antibody-mediated inhibition of syndecan-4 dimerisation reduces interleukin (IL)-1 receptor trafficking and signalling
Lars Godmann, Miriam Bollmann, Adelheid Korb-Pap, Ulrich König, Joanna Sherwood, Denise Beckmann, Katja Mühlenberg, Frank Echtermeyer, James Whiteford, Giulia De Rossi, Thomas Pap, Jessica Bertrand

Annals of the Rheumatic Diseases Apr 2020, 79 (4) 481-489; DOI: 10.1136/annrheumdis-2019-216847
Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH
Christopher W Wasson, Giuseppina Abignano, Heidi Hermes, Maya Malaab, Rebecca L Ross, Sergio A Jimenez, Howard Y Chang, Carol A Feghali-Bostwick, Francesco del Galdo

Annals of the Rheumatic Diseases Apr 2020, 79 (4) 507-517; DOI: 10.1136/annrheumdis-2019-216542
Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration
Hao Sun, Xingzhao Wen, Hongyi Li, Peihui Wu, Minghui Gu, Xiaoyi Zhao, Ziji Zhang, Shu Hu, Guping Mao, Ruofan Ma, Weiming Liao, Zhiqi Zhang

Annals of the Rheumatic Diseases Mar 2020, 79 (3) 408-417; DOI: 10.1136/annrheumdis-2019-215926
Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts
Meng Sun, Bence Rethi, Akilan Krishnamurthy, Vijay Joshua, Alexandra Circiumaru, Aase Haj Hensvold, Elena Ossipova, Caroline Grönwall, Yanying Liu, Marianne Engstrom, Sergiu Bogdan Catrina, Johanna Steen, Vivianne Malmstrom, Lars Klareskog, Camilla Svensson, Caroline Ospelt, Heidi Wähämaa, Anca Irinel Catrina

Annals of the Rheumatic Diseases Dec 2019, 78 (12) 1621-1631; DOI: 10.1136/annrheumdis-2018-214967
CD109 regulates the inflammatory response and is required for the pathogenesis of rheumatoid arthritis
Guanhua Song, Tingting Feng, Ru Zhao, Qiqi Lu, Yutao Diao, Qingwei Guo, Zhaoxia Wang, Yuang Zhang, Luna Ge, Jihong Pan, Lin Wang, Jinxiang Han

Annals of the Rheumatic Diseases Dec 2019, 78 (12) 1632-1641; DOI: 10.1136/annrheumdis-2019-215473
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs
Alexandru-Emil Matei, Chih-Wei Chen, Lisa Kiesewetter, Andrea-Hermina Györfi, Yi-Nan Li, Thuong Trinh-Minh, Xiaohan Xu, Cuong Tran Manh, Toin van Kuppevelt, Jan Hansmann, Astrid Jüngel, Georg Schett, Florian Groeber-Becker, Jörg H W Distler

Annals of the Rheumatic Diseases Dec 2019, 78 (12) 1686-1692; DOI: 10.1136/annrheumdis-2019-216108
Interferon regulatory factor 7 (IRF7) represents a link between inflammation and fibrosis in the pathogenesis of systemic sclerosis
Minghua Wu, Brian Skaug, Xiongjie Bi, Tingting Mills, Gloria Salazar, Xiaodong Zhou, John Reveille, Sandeep K Agarwal, Michael R Blackburn, Maureen D Mayes, Shervin Assassi

Annals of the Rheumatic Diseases Nov 2019, 78 (11) 1583-1591; DOI: 10.1136/annrheumdis-2019-215208

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