Fibroblasts

TGFβ promotes low IL10-producing ILC2 with profibrotic ability involved in skin fibrosis in systemic sclerosis
Paôline Laurent, Benoit Allard, Pauline Manicki, Valérie Jolivel, Emeline Levionnois, Mohamed Jeljeli, Pauline Henrot, Julien Izotte, Damien Leleu, Alexis Groppi, Julien Seneschal, Joel Constans, Carlo Chizzolini, Christophe Richez, Pierre Duffau, Estibaliz Lazaro, Edouard Forcade, Thierry Schaeverbeke, Thomas Pradeu, Frédéric Batteux, Patrick Blanco, Cécile Contin-Bordes, Marie-Elise Truchetet

Annals of the Rheumatic Diseases Jul 2021, annrheumdis-2020-219748; DOI: 10.1136/annrheumdis-2020-219748
X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc)
Christina Bergmann, Ludwig Hallenberger, Sara Chenguiti Fakhouri, Benita Merlevede, Amelie Brandt, Clara Dees, Honglin Zhu, Ariella Zehender, Xiang Zhou, Annemarie Schwab, Chih-Wei Chen, Andrea Hermina Györfi, Alexandru Emil Matei, Debomita Chakraborty, Thuong Trinh-Minh, Simon Rauber, Roland Coras, Aline Bozec, Alexander Kreuter, Mirjana Ziemer, Georg Schett, Jörg H W Distler

Annals of the Rheumatic Diseases Aug 2021, 80 (8) 1048-1056; DOI: 10.1136/annrheumdis-2020-219822
Tenascin-C-mediated suppression of extracellular matrix adhesion force promotes entheseal new bone formation through activation of Hippo signalling in ankylosing spondylitis
Zihao Li, Siwen Chen, Haowen Cui, Xiang Li, Dongying Chen, Wenjun Hao, Jianru Wang, Zemin Li, Zhaomin Zheng, Zhongping Zhang, Hui Liu

Annals of the Rheumatic Diseases Jul 2021, 80 (7) 891-902; DOI: 10.1136/annrheumdis-2021-220002
Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis
Haruka Tsuchiya, Mineto Ota, Shuji Sumitomo, Kazuyoshi Ishigaki, Akari Suzuki, Toyonori Sakata, Yumi Tsuchida, Hiroshi Inui, Jun Hirose, Yuta Kochi, Yuho Kadono, Katsuhiko Shirahige, Sakae Tanaka, Kazuhiko Yamamoto, Keishi Fujio

Annals of the Rheumatic Diseases Apr 2021, 80 (4) 440-450; DOI: 10.1136/annrheumdis-2020-218189
Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement
Kimberly Showalter, Robert Spiera, Cynthia Magro, Phaedra Agius, Viktor Martyanov, Jennifer M Franks, Roshan Sharma, Heather Geiger, Tammara A Wood, Yaxia Zhang, Caryn R Hale, Jackie Finik, Michael L Whitfield, Dana E Orange, Jessica K Gordon

Annals of the Rheumatic Diseases Feb 2021, 80 (2) 228-237; DOI: 10.1136/annrheumdis-2020-217840
Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis
Anke J Roelofs, Karolina Kania, Alexandra J Rafipay, Meike Sambale, Stephanie T Kuwahara, Fraser L Collins, Joanna Smeeton, Maxwell A Serowoky, Lynn Rowley, Hui Wang, René Gronewold, Chrysa Kapeni, Simón Méndez-Ferrer, Christopher B Little, John F Bateman, Thomas Pap, Francesca V Mariani, Joanna Sherwood, J Gage Crump, Cosimo De Bari

Annals of the Rheumatic Diseases Dec 2020, 79 (12) 1625-1634; DOI: 10.1136/annrheumdis-2020-218350
Response to: ‘Correspondence on ‘Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement’’ by Manetti
Kimberly Showalter, Cynthia Magro, Yaxia Zhang, Robert Spiera, Dana E Orange, Jessica K Gordon

Annals of the Rheumatic Diseases Nov 2020, annrheumdis-2020-219292; DOI: 10.1136/annrheumdis-2020-219292
Correspondence on ‘Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement’
Mirko Manetti

Annals of the Rheumatic Diseases Nov 2020, annrheumdis-2020-219264; DOI: 10.1136/annrheumdis-2020-219264
Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging
Christian Schmidkonz, Simon Rauber, Armin Atzinger, Rahul Agarwal, Theresa Ida Götz, Alina Soare, Michael Cordes, Olaf Prante, Christina Bergmann, Arnd Kleyer, Philipp Ritt, Simone Maschauer, Peter Hennig, Johannes Toms, Markus Köhner, Bernhard Manger, John H Stone, Uwe Haberkorn, Tobias Baeuerle, Jörg H W Distler, Abbas Agaimy, Torsten Kuwert, Georg Schett, Andreas Ramming

Annals of the Rheumatic Diseases Nov 2020, 79 (11) 1485-1491; DOI: 10.1136/annrheumdis-2020-217408
‘Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients’
Maya H Buch, Andrew Melville, Dennis G McGonagle

Annals of the Rheumatic Diseases Nov 2020, 79 (11) e140; DOI: 10.1136/annrheumdis-2019-215881

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