Fibroblasts

Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement
Kimberly Showalter, Robert Spiera, Cynthia Magro, Phaedra Agius, Viktor Martyanov, Jennifer M Franks, Roshan Sharma, Heather Geiger, Tammara A Wood, Yaxia Zhang, Caryn R Hale, Jackie Finik, Michael L Whitfield, Dana E Orange, Jessica K Gordon

Annals of the Rheumatic Diseases Feb 2021, 80 (2) 228-237; DOI: 10.1136/annrheumdis-2020-217840
Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis
Anke J Roelofs, Karolina Kania, Alexandra J Rafipay, Meike Sambale, Stephanie T Kuwahara, Fraser L Collins, Joanna Smeeton, Maxwell A Serowoky, Lynn Rowley, Hui Wang, René Gronewold, Chrysa Kapeni, Simón Méndez-Ferrer, Christopher B Little, John F Bateman, Thomas Pap, Francesca V Mariani, Joanna Sherwood, J Gage Crump, Cosimo De Bari

Annals of the Rheumatic Diseases Dec 2020, 79 (12) 1625-1634; DOI: 10.1136/annrheumdis-2020-218350
Response to: ‘Correspondence on ‘Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement’’ by Manetti
Kimberly Showalter, Cynthia Magro, Yaxia Zhang, Robert Spiera, Dana E Orange, Jessica K Gordon

Annals of the Rheumatic Diseases Nov 2020, annrheumdis-2020-219292; DOI: 10.1136/annrheumdis-2020-219292
Correspondence on ‘Machine learning integration of scleroderma histology and gene expression identifies fibroblast polarisation as a hallmark of clinical severity and improvement’
Mirko Manetti

Annals of the Rheumatic Diseases Nov 2020, annrheumdis-2020-219264; DOI: 10.1136/annrheumdis-2020-219264
Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis
Haruka Tsuchiya, Mineto Ota, Shuji Sumitomo, Kazuyoshi Ishigaki, Akari Suzuki, Toyonori Sakata, Yumi Tsuchida, Hiroshi Inui, Jun Hirose, Yuta Kochi, Yuho Kadono, Katsuhiko Shirahige, Sakae Tanaka, Kazuhiko Yamamoto, Keishi Fujio

Annals of the Rheumatic Diseases Nov 2020, annrheumdis-2020-218189; DOI: 10.1136/annrheumdis-2020-218189
Disentangling inflammatory from fibrotic disease activity by fibroblast activation protein imaging
Christian Schmidkonz, Simon Rauber, Armin Atzinger, Rahul Agarwal, Theresa Ida Götz, Alina Soare, Michael Cordes, Olaf Prante, Christina Bergmann, Arnd Kleyer, Philipp Ritt, Simone Maschauer, Peter Hennig, Johannes Toms, Markus Köhner, Bernhard Manger, John H Stone, Uwe Haberkorn, Tobias Baeuerle, Jörg H W Distler, Abbas Agaimy, Torsten Kuwert, Georg Schett, Andreas Ramming

Annals of the Rheumatic Diseases Nov 2020, 79 (11) 1485-1491; DOI: 10.1136/annrheumdis-2020-217408
‘Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients’
Maya H Buch, Andrew Melville, Dennis G McGonagle

Annals of the Rheumatic Diseases Nov 2020, 79 (11) e140; DOI: 10.1136/annrheumdis-2019-215881
PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis
Yun Zhang, Lichong Shen, Honglin Zhu, Katja Dreissigacker, Diana Distler, Xiang Zhou, Andrea Hermina Györfi, Christina Bergmann, Xianyi Meng, Clara Dees, Thuong Trinh-Minh, Ingo Ludolph, Raymund Horch, Andreas Ramming, Georg Schett, Jörg H W Distler

Annals of the Rheumatic Diseases Sep 2020, 79 (9) 1227-1233; DOI: 10.1136/annrheumdis-2020-216963
Could autologous adipose-derived stromal vascular fraction turn out an unwanted source of profibrotic myofibroblasts in systemic sclerosis?
Mirko Manetti

Annals of the Rheumatic Diseases May 2020, 79 (5) e55; DOI: 10.1136/annrheumdis-2019-215288
Antibody-mediated inhibition of syndecan-4 dimerisation reduces interleukin (IL)-1 receptor trafficking and signalling
Lars Godmann, Miriam Bollmann, Adelheid Korb-Pap, Ulrich König, Joanna Sherwood, Denise Beckmann, Katja Mühlenberg, Frank Echtermeyer, James Whiteford, Giulia De Rossi, Thomas Pap, Jessica Bertrand

Annals of the Rheumatic Diseases Apr 2020, 79 (4) 481-489; DOI: 10.1136/annrheumdis-2019-216847

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