Cytokines

Dysregulated neutrophil responses and neutrophil extracellular trap formation and degradation in PAPA syndrome
Pragnesh Mistry, Carmelo Carmona-Rivera, Amanda K Ombrello, Patrycja Hoffmann, Nickie L Seto, Anne Jones, Deborah L Stone, Faiza Naz, Philip Carlucci, Stefania Dell’Orso, Gustavo Gutierrez-Cruz, Hong-Wei Sun, Daniel L Kastner, Ivona Aksentijevich, Mariana J Kaplan

Annals of the Rheumatic Diseases Dec 2018, 77 (12) 1825-1833; DOI: 10.1136/annrheumdis-2018-213746
Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis
Richard Conway, Lorraine O’Neill, Geraldine M McCarthy, Conor C Murphy, Aurelie Fabre, Susan Kennedy, Douglas J Veale, Sarah M Wade, Ursula Fearon, Eamonn S Molloy

Annals of the Rheumatic Diseases Dec 2018, 77 (12) 1815-1824; DOI: 10.1136/annrheumdis-2018-213488
Response to e-letter: ‘Tocilizumab in patients with adult-onset Still’s disease refractory to glucocorticoid treatment’ by Lee
Yuko Kaneko, Hideto Kameda, Kei Ikeda, Tomonori Ishii, Kosaku Murakami, Hyota Takamatsu, Yoshiya Tanaka, Takayuki Abe, Tsutomu Takeuchi

Annals of the Rheumatic Diseases Nov 2018, annrheumdis-2018-214653; DOI: 10.1136/annrheumdis-2018-214653
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa
Mrinal K Sarkar, Grace A Hile, Lam C Tsoi, Xianying Xing, Jianhua Liu, Yun Liang, Celine C Berthier, William R Swindell, Matthew T Patrick, Shuai Shao, Pei-Suen Tsou, Ranjitha Uppala, Maria A Beamer, Anshika Srivastava, Stephanie L Bielas, Paul W Harms, Spiro Getsios, James T Elder, John J Voorhees, Johann E Gudjonsson, J Michelle Kahlenberg

Annals of the Rheumatic Diseases Nov 2018, 77 (11) 1653-1664; DOI: 10.1136/annrheumdis-2018-213197
Why did IL-23p19 inhibition fail in AS: a tale of tissues, trials or translation?
Stefan Siebert, Neal L Millar, Iain B McInnes

Annals of the Rheumatic Diseases Oct 2018, annrheumdis-2018-213654; DOI: 10.1136/annrheumdis-2018-213654
Non-classical monocytes as mediators of tissue destruction in arthritis
Antonia Puchner, Victoria Saferding, Michael Bonelli, Yohei Mikami, Melanie Hofmann, Julia S Brunner, Michael Caldera, Eliana Goncalves-Alves, Nikolaus B Binder, Anita Fischer, Elisabeth Simader, Carl-Walter Steiner, Harald Leiss, Silvia Hayer, Birgit Niederreiter, Thomas Karonitsch, Marije I Koenders, Bruno K Podesser, John J O’Shea, Jörg Menche, Josef S Smolen, Kurt Redlich, Stephan Blüml

Annals of the Rheumatic Diseases Oct 2018, 77 (10) 1490-1497; DOI: 10.1136/annrheumdis-2018-213250
Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status
Md Yuzaiful Md Yusof, Antonios Psarras, Yasser M El-Sherbiny, Elizabeth M A Hensor, Katherine Dutton, Sabih Ul-Hassan, Ahmed S Zayat, Mohammad Shalbaf, Adewonuola Alase, Miriam Wittmann, Paul Emery, Edward M Vital

Annals of the Rheumatic Diseases Oct 2018, 77 (10) 1432-1439; DOI: 10.1136/annrheumdis-2018-213386
Apoptosis-derived membrane vesicles drive the cGAS–STING pathway and enhance type I IFN production in systemic lupus erythematosus
Yasuhiro Kato, JeongHoon Park, Hyota Takamatsu, Hachirou Konaka, Wataru Aoki, Syunsuke Aburaya, Mitsuyoshi Ueda, Masayuki Nishide, Shohei Koyama, Yoshitomo Hayama, Yuhei Kinehara, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Annals of the Rheumatic Diseases Oct 2018, 77 (10) 1507-1515; DOI: 10.1136/annrheumdis-2018-212988
Aortic ulceration in a tocilizumab-treated patient with Takayasu arteritis
Emily J Liebling, Rosemary Peterson, Teresa Victoria, Jon M Burnham

Annals of the Rheumatic Diseases Aug 2018, annrheumdis-2018-214191; DOI: 10.1136/annrheumdis-2018-214191
Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis
Christopher P Denton, Voon H Ong, Shiwen Xu, Haiyin Chen-Harris, Zora Modrusan, Robert Lafyatis, Dinesh Khanna, Angelika Jahreis, Jeffrey Siegel, Thierry Sornasse

Annals of the Rheumatic Diseases Sep 2018, 77 (9) 1362-1371; DOI: 10.1136/annrheumdis-2018-213031

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