Cytokines

Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis
Richard Conway, Lorraine O’Neill, Geraldine M McCarthy, Conor C Murphy, Aurelie Fabre, Susan Kennedy, Douglas J Veale, Sarah M Wade, Ursula Fearon, Eamonn S Molloy

Annals of the Rheumatic Diseases Aug 2018, annrheumdis-2018-213488; DOI: 10.1136/annrheumdis-2018-213488
Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis
Christopher P Denton, Voon H Ong, Shiwen Xu, Haiyin Chen-Harris, Zora Modrusan, Robert Lafyatis, Dinesh Khanna, Angelika Jahreis, Jeffrey Siegel, Thierry Sornasse

Annals of the Rheumatic Diseases Sep 2018, 77 (9) 1362-1371; DOI: 10.1136/annrheumdis-2018-213031
CC-chemokine ligand 18 is a useful biomarker associated with disease activity in IgG4-related disease
Mitsuhiro Akiyama, Hidekata Yasuoka, Keiko Yoshimoto, Tsutomu Takeuchi

Annals of the Rheumatic Diseases Sep 2018, 77 (9) 1386-1387; DOI: 10.1136/annrheumdis-2017-212110
Urinary epidermal growth factor predicts renal prognosis in antineutrophil cytoplasmic antibody-associated vasculitis
Liang Wu, Xiao-Qian Li, Tanvi Goyal, Sean Eddy, Matthias Kretzler, Wen-Jun Ju, Min Chen, Ming-Hui Zhao

Annals of the Rheumatic Diseases Sep 2018, 77 (9) 1339-1344; DOI: 10.1136/annrheumdis-2017-212578
Expansion of T follicular helper-T helper 1 like cells through epigenetic regulation by signal transducer and activator of transcription factors
Xiaoxue Ma, Shingo Nakayamada, Satoshi Kubo, Kei Sakata, Kaoru Yamagata, Yusuke Miyazaki, Maiko Yoshikawa, Yukihiro Kitanaga, Mingzeng Zhang, Yoshiya Tanaka

Annals of the Rheumatic Diseases Sep 2018, 77 (9) 1354-1361; DOI: 10.1136/annrheumdis-2017-212652
Role of tubulointerstitial injury in ANCA-associated vasculitis is underestimated
Nikolai Bulanov, Natalia V Chebotareva, Pavel I Novikov, Sergey V Moiseev

Annals of the Rheumatic Diseases Jul 2018, annrheumdis-2018-214095; DOI: 10.1136/annrheumdis-2018-214095
Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status
Md Yuzaiful Md Yusof, Antonios Psarras, Yasser M El-Sherbiny, Elizabeth M A Hensor, Katherine Dutton, Sabih Ul-Hassan, Ahmed S Zayat, Mohammad Shalbaf, Adewonuola Alase, Miriam Wittmann, Paul Emery, Edward M Vital

Annals of the Rheumatic Diseases Jul 2018, annrheumdis-2018-213386; DOI: 10.1136/annrheumdis-2018-213386
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa
Mrinal K Sarkar, Grace A Hile, Lam C Tsoi, Xianying Xing, Jianhua Liu, Yun Liang, Celine C Berthier, William R Swindell, Matthew T Patrick, Shuai Shao, Pei-Suen Tsou, Ranjitha Uppala, Maria A Beamer, Anshika Srivastava, Stephanie L Bielas, Paul W Harms, Spiro Getsios, James T Elder, John J Voorhees, Johann E Gudjonsson, J Michelle Kahlenberg

Annals of the Rheumatic Diseases Jul 2018, annrheumdis-2018-213197; DOI: 10.1136/annrheumdis-2018-213197
Non-classical monocytes as mediators of tissue destruction in arthritis
Antonia Puchner, Victoria Saferding, Michael Bonelli, Yohei Mikami, Melanie Hofmann, Julia S Brunner, Michael Caldera, Eliana Goncalves-Alves, Nikolaus B Binder, Anita Fischer, Elisabeth Simader, Carl-Walter Steiner, Harald Leiss, Silvia Hayer, Birgit Niederreiter, Thomas Karonitsch, Marije I Koenders, Bruno K Podesser, John J O’Shea, Jörg Menche, Josef S Smolen, Kurt Redlich, Stephan Blüml

Annals of the Rheumatic Diseases Jun 2018, annrheumdis-2018-213250; DOI: 10.1136/annrheumdis-2018-213250
Apoptosis-derived membrane vesicles drive the cGAS–STING pathway and enhance type I IFN production in systemic lupus erythematosus
Yasuhiro Kato, JeongHoon Park, Hyota Takamatsu, Hachirou Konaka, Wataru Aoki, Syunsuke Aburaya, Mitsuyoshi Ueda, Masayuki Nishide, Shohei Koyama, Yoshitomo Hayama, Yuhei Kinehara, Toru Hirano, Yoshihito Shima, Masashi Narazaki, Atsushi Kumanogoh

Annals of the Rheumatic Diseases Jun 2018, annrheumdis-2018-212988; DOI: 10.1136/annrheumdis-2018-212988

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