Chondrocytes

NAMPT (visfatin), a direct target of hypoxia-inducible factor-2α, is an essential catabolic regulator of osteoarthritis
Siyoung Yang, Je-Hwang Ryu, Hwanhee Oh, Jimin Jeon, Ji-Sun Kwak, Jin-Hong Kim, Hyun Ah Kim, Churl-Hong Chun, Jang-Soo Chun

Annals of the Rheumatic Diseases Mar 2015, 74 (3) 595-602; DOI: 10.1136/annrheumdis-2013-204355
Articular chondrocyte network mediated by gap junctions: role in metabolic cartilage homeostasis
Maria D Mayan, Raquel Gago-Fuentes, Paula Carpintero-Fernandez, Patricia Fernandez-Puente, Purificacion Filgueira-Fernandez, Noa Goyanes, Virginijus Valiunas, Peter R Brink, Gary S Goldberg, Francisco J Blanco

Annals of the Rheumatic Diseases Jan 2015, 74 (1) 275-284; DOI: 10.1136/annrheumdis-2013-204244
Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo
Shouan Zhu, Ping Lu, Huanhuan Liu, Pengfei Chen, Yan Wu, Yanyan Wang, Heng Sun, Xiaolei Zhang, Qingqing Xia, Boon Chin Heng, Yiting Zhou, Hong Wei Ouyang

Annals of the Rheumatic Diseases Jan 2015, 74 (1) 285-293; DOI: 10.1136/annrheumdis-2013-203901
Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches
W den Hollander, Y F M Ramos, S D Bos, N Bomer, R van der Breggen, N Lakenberg, W J de Dijcker, Bouke J Duijnisveld, P E Slagboom, Rob G H H Nelissen, I Meulenbelt

Annals of the Rheumatic Diseases Dec 2014, 73 (12) 2208-2212; DOI: 10.1136/annrheumdis-2014-205980
Disease-modifying effects of TD-198946 on progressed osteoarthritis in a mouse model
Fumiko Yano, Shinsuke Ohba, Yoko Hosaka, Taku Saito, Ung-il Chung

Annals of the Rheumatic Diseases Nov 2014, 73 (11) 2062-2064; DOI: 10.1136/annrheumdis-2014-205672
Interphalangeal Osteoarthritis Radiographic Simplified (iOARS) score: a radiographic method to detect osteoarthritis of the interphalangeal finger joints based on its histopathological alterations
Ilse-Gerlinde Sunk, Love Amoyo-Minar, Tanja Stamm, Stefanie Haider, Birgit Niederreiter, Gabriela Supp, Afschin Soleiman, Franz Kainberger, Josef S Smolen, Klaus Bobacz

Annals of the Rheumatic Diseases Nov 2014, 73 (11) 1983-1989; DOI: 10.1136/annrheumdis-2012-203117
Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice
Min-jun Huang, Liang Wang, Da-di Jin, Zhong-min Zhang, Tian-yu Chen, Chun-hong Jia, Yan Wang, Xiao-chen Zhen, Bin Huang, Bo Yan, Yu-hui Chen, Sheng-fa Li, Jin-cheng Yang, Yi-fan Dai, Xiao-chun Bai

Annals of the Rheumatic Diseases Sep 2014, 73 (9) 1719-1727; DOI: 10.1136/annrheumdis-2013-203231
ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis
Yongjie Lai, Xiaohui Bai, Yunpeng Zhao, Qingyun Tian, Ben Liu, Edward A Lin, Yuqing Chen, Brendan Lee, C Thomas Appleton, Frank Beier, Xiu-Ping Yu, Chuan-ju Liu

Annals of the Rheumatic Diseases Aug 2014, 73 (8) 1575-1584; DOI: 10.1136/annrheumdis-2013-203561
Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice
Tokio Matsuzaki, Takehiko Matsushita, Koji Takayama, Tomoyuki Matsumoto, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka

Annals of the Rheumatic Diseases Jul 2014, 73 (7) 1397-1404; DOI: 10.1136/annrheumdis-2012-202620
Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence
Raewyn C Poulsen, Anna C Watts, Richard J Murphy, Sarah J Snelling, Andrew J Carr, Philippa A Hulley

Annals of the Rheumatic Diseases Jul 2014, 73 (7) 1405-1413; DOI: 10.1136/annrheumdis-2012-203146

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