Chondrocytes

Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice
Min-jun Huang, Liang Wang, Da-di Jin, Zhong-min Zhang, Tian-yu Chen, Chun-hong Jia, Yan Wang, Xiao-chen Zhen, Bin Huang, Bo Yan, Yu-hui Chen, Sheng-fa Li, Jin-cheng Yang, Yi-fan Dai, Xiao-chun Bai

Annals of the Rheumatic Diseases Sep 2014, 73 (9) 1719-1727; DOI: 10.1136/annrheumdis-2013-203231
ADAMTS-7 forms a positive feedback loop with TNF-α in the pathogenesis of osteoarthritis
Yongjie Lai, Xiaohui Bai, Yunpeng Zhao, Qingyun Tian, Ben Liu, Edward A Lin, Yuqing Chen, Brendan Lee, C Thomas Appleton, Frank Beier, Xiu-Ping Yu, Chuan-ju Liu

Annals of the Rheumatic Diseases Aug 2014, 73 (8) 1575-1584; DOI: 10.1136/annrheumdis-2013-203561
Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice
Tokio Matsuzaki, Takehiko Matsushita, Koji Takayama, Tomoyuki Matsumoto, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka

Annals of the Rheumatic Diseases Jul 2014, 73 (7) 1397-1404; DOI: 10.1136/annrheumdis-2012-202620
Glucocorticoids induce senescence in primary human tenocytes by inhibition of sirtuin 1 and activation of the p53/p21 pathway: in vivo and in vitro evidence
Raewyn C Poulsen, Anna C Watts, Richard J Murphy, Sarah J Snelling, Andrew J Carr, Philippa A Hulley

Annals of the Rheumatic Diseases Jul 2014, 73 (7) 1405-1413; DOI: 10.1136/annrheumdis-2012-203146
Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients
Juan Fernández-Tajes, Angel Soto-Hermida, Maria E Vázquez-Mosquera, Estefania Cortés-Pereira, Alejandro Mosquera, Mercedes Fernández-Moreno, Natividad Oreiro, Carlos Fernández-López, Jose Luis Fernández, Ignacio Rego-Pérez, Francisco J Blanco

Annals of the Rheumatic Diseases Apr 2014, 73 (4) 668-677; DOI: 10.1136/annrheumdis-2012-202783
Differential expression of adipokines in infrapatellar fat pad (IPFP) and synovium of osteoarthritis patients and healthy individuals
Javier Conde, Morena Scotece, Verónica López, Vanessa Abella, Miguel Hermida, Jesús Pino, Francisca Lago, Juan J Gómez-Reino, Oreste Gualillo

Annals of the Rheumatic Diseases Mar 2014, 73 (3) 631-633; DOI: 10.1136/annrheumdis-2013-204189
Relationship between the functional exon 3 deleted growth hormone receptor polymorphism and symptomatic osteoarthritis in women
K M J A Claessen, M Kloppenburg, H M Kroon, J Bijsterbosch, A M Pereira, J A Romijn, T van der Straaten, R G H H Nelissen, A Hofman, A G Uitterlinden, B J Duijnisveld, N Lakenberg, M Beekman, J B van Meurs, P E Slagboom, N R Biermasz, I Meulenbelt

Annals of the Rheumatic Diseases Feb 2014, 73 (2) 433-436; DOI: 10.1136/annrheumdis-2012-202713
Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone
Andrew J Preston, Craig M Keenan, Hazel Sutherland, Peter J Wilson, Brenda Wlodarski, Adam M Taylor, Dominic P Williams, Lakshminarayan R Ranganath, James A Gallagher, Jonathan C Jarvis

Annals of the Rheumatic Diseases Jan 2014, 73 (1) 284-289; DOI: 10.1136/annrheumdis-2012-202878
Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration
Kate Louise Eve Phillips, Nikki Jordan-Mahy, Martin J H Nicklin, Christine Lyn Le Maitre

Annals of the Rheumatic Diseases Nov 2013, 72 (11) 1860-1867; DOI: 10.1136/annrheumdis-2012-202266
Interleukin-6 acts locally on the growth plate to impair bone growth
Paola Fernandez-Vojvodich, Farasat Zaman, Lars Sävendahl

Annals of the Rheumatic Diseases Oct 2013, 72 (10) e24; DOI: 10.1136/annrheumdis-2013-204112

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