Chondrocytes

Oncostatin M in combination with tumour necrosis factor α induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2
W Hui, H E Barksby, D A Young, T E Cawston, N McKie, A D Rowan

Annals of the Rheumatic Diseases Nov 2005, 64 (11) 1624-1632; DOI: 10.1136/ard.2004.028191
Basic calcium phosphate crystals activate human osteoarthritic synovial fibroblasts and induce matrix metalloproteinase-13 (collagenase-3) in adult porcine articular chondrocytes
G M McCarthy, P R Westfall, I Masuda, P A Christopherson, H S Cheung, P G Mitchell

Annals of the Rheumatic Diseases Apr 2001, 60 (4) 399-406; DOI: 10.1136/ard.60.4.399
Interleukin 13 blocks the release of collagen from bovine nasal cartilage treated with proinflammatory cytokines
C S Cleaver, A D Rowan, T E Cawston

Annals of the Rheumatic Diseases Feb 2001, 60 (2) 150-157; DOI: 10.1136/ard.60.2.150
circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1
Shuying Shen, Yute Yang, Panyang Shen, Jun Ma, Bin Fang, Qingxin Wang, Kefan Wang, Peihua Shi, Shunwu Fan, Xiangqian Fang

Annals of the Rheumatic Diseases Sep 2021, 80 (9) 1209-1219; DOI: 10.1136/annrheumdis-2021-219969
A novel disease-modifying osteoarthritis drug candidate targeting Runx1
Fumiko Yano, Hironori Hojo, Shinsuke Ohba, Atsushi Fukai, Yoko Hosaka, Toshiyuki Ikeda, Taku Saito, Makoto Hirata, Hirotaka Chikuda, Tsuyoshi Takato, Hiroshi Kawaguchi, Ung-il Chung

Annals of the Rheumatic Diseases May 2013, 72 (5) 748-753; DOI: 10.1136/annrheumdis-2012-201745
Metformin limits osteoarthritis development and progression through activation of AMPK signalling
Jun Li, Bin Zhang, Wei-Xiao Liu, Ke Lu, Haobo Pan, Tingyu Wang, Chun-do Oh, Dan Yi, Jian Huang, Lan Zhao, Guangzhi Ning, Cong Xing, Guozhi Xiao, Ru Liu-Bryan, Shiqing Feng, Di Chen

Annals of the Rheumatic Diseases May 2020, 79 (5) 635-645; DOI: 10.1136/annrheumdis-2019-216713
Serum NT/CT SIRT1 ratio reflects early osteoarthritis and chondrosenescence
George Batshon, Jinan Elayyan, Omar Qiq, Eli Reich, Louisa Ben-Aderet, Leonid Kandel, Amir Haze, Jürgen Steinmeyer, Veronique Lefebvre, Hong Zhang, Jennifer Elisseeff, Yves Henrotin, Ali Mobasheri, Mona Dvir-Ginzberg

Annals of the Rheumatic Diseases Oct 2020, 79 (10) 1370-1380; DOI: 10.1136/annrheumdis-2020-217072
Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice
Tokio Matsuzaki, Takehiko Matsushita, Koji Takayama, Tomoyuki Matsumoto, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka

Annals of the Rheumatic Diseases Jul 2014, 73 (7) 1397-1404; DOI: 10.1136/annrheumdis-2012-202620
Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2
Haiyan Zhang, Chuangxin Lin, Chun Zeng, Zhenyu Wang, Hua Wang, Jiansen Lu, Xin Liu, Yan Shao, Chang Zhao, Jianying Pan, Song Xu, Yue Zhang, Denghui Xie, Daozhang Cai, Xiaochun Bai

Annals of the Rheumatic Diseases Oct 2018, 77 (10) 1524-1534; DOI: 10.1136/annrheumdis-2018-213450
Stratification of knee osteoarthritis: two major patient subgroups identified by genome-wide expression analysis of articular cartilage
Jamie Soul, Sara L Dunn, Sanjay Anand, Ferdinand Serracino-Inglott, Jean-Marc Schwartz, Ray P Boot-Handford, Tim E Hardingham

Annals of the Rheumatic Diseases Mar 2018, 77 (3) 423; DOI: 10.1136/annrheumdis-2017-212603

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