Examples of organ/life-threatening and not organ/life-threatening manifestations in patients with AAV
| Examples of potentially organ/life-threatening manifestations* | Examples of manifestations that are not ultimately organ/life-threatening* |
| Glomerulonephritis | Nasal and paranasal disease without bony involvement (erosion) or cartilage collapse or olfactory dysfunction or deafness |
| Pulmonary haemorrhage | Skin involvement without ulceration |
| Meningeal involvement | Myositis (skeletal muscle only) |
| Central nervous system involvement | Non-cavitating pulmonary nodules |
| Retro-orbital disease | Episcleritis |
| Cardiac involvement | |
| Mesenteric involvement | |
| Mononeuritis multiplex |
*These are just examples of typical disease manifestations and many other manifestations of AAV exist. Assessment of severity in the individual patient may differ (eg, scleritis can become organ threatening under certain circumstances).
AAV, antineutrophil cytoplasmic antibody-associated vasculitis.