Table 1

Clinical data of patients regarding fulfilling 1990 ACR CSS classification criteria and 2017 ACR/EULAR Draft Criteria for EGPA

1990 ACR CCS classification criteria (4/6 for classification)14 Case 1Case 2Draft ACR/EULAR Criteria for EGPA
(>5 points for classification)15
Case 1 (total score: 8)Case 2 (total score: 11)
AsthmaYesYesObstructive airways disease (+3)+3+3
Paranasal sinus abnormalityYes NoNasal polyps (+3) No+3
Mononeuropathy (including multiplex) or polyneuropathy No NoMononeuritis multiplex or motor neuropathy (+1)NoNo
Eosinophilia >10% on differential white blood cell countYesYesEosinophil count >109/mL (+5)+5+5
Biopsy containing a blood vessel with extravascular eosinophilsNot done Not done Extravascular eosinophil predominant inflammation/increased eosinophils in bone marrow (2) Not doneNot done 
Non‐fixed pulmonary infiltrates on roentgenographyYesYes
Microscopic haematuria (−1)NoNo
c-ANCA or PR3-antibody positivity (−3)NegativeNegative
  • ACR, American College of Rheumatology; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibody; CSS, Churg-Strauss syndrome; EGPA, eosinophilic granulomatosis with polyangiitis; EULAR, European League Against Rheumatism.