Comparisons of the number of non-survivors according to features at admission between patients treated with colchicine + SoC or with SoC only5
Features at admission | Non-survivors Colchicine±SoC | Non-survivors SoC | P |
Ferritin <300 ng/mL | 1/9 (11%) | 7/24 (29%) | 0.39 |
Ferritin >300 ng/mL | 16/93 (17%) | 35/87 (40%) | <0.01 |
PaO2/FiO2 >300 mm Hg/% | 0/6 | 3/32 (9%) | 1.0 |
PaO2/FiO2 300–201 mm Hg/% (mild ARDS) | 2/42 (4%) | 9/44 (20%) | 0.049 |
PaO2/FiO2 200–101 mm Hg/% (moderate ARDS) | 5/31 (16%) | 17/24 (71%) | <0.01 |
PaO2/FiO2 ≤100 mm Hg/% (severe ARDS) | 6/24 (25%) | 8/11 (73%) | 0.01 |
Number of non-survivors/number of subjects in the two groups.
ARDS, Acute Respiratory Distress Syndrome; ; FiO2, fractional inspired oxygen; PaO2, arterial oxygen tension (or pressure); SoC, Standard of Care.