Multivariable stratified analyses for the risk of SLE associated with ITP or AIHA exposure in the propensity-score matched (1:2) populations
| ITP | AIHA | |||||||||
| Non-ITP | ITP | HR (95% CI) | P value | P for interaction | Non-AIHA | AIHA | HR (95% CI) | P value | P for interaction | |
| No. of events/total no. of patients (per 105 person months) | No. of events/total no. of patients (per 105 person months) | |||||||||
| Overall | 5/6358 (1.36) | 307/3179 (197.44) | 135.91 (56.16 to 328.92) | <0.001 | 4/1828 (3.96) | 138/914 (357.31) | 83.96 (31.03 to 227.21) | <0.001 | ||
| Age (years) | 0.966 | 0.376 | ||||||||
| <65 | 5/4479 (1.82) | 280/2246 (239.92) | 124.33 (51.34 to 301.11) | <0.001 | 3/1100 (4.45) | 122/552 (472.11) | 103.83 (32.93 to 327.37) | <0.001 | ||
| ≥65 | 0/1879 (0.00) | 27/933 (69.61) | Cannot estimate | 0.988 | 1/728 (2.96) | 16/362 (125.19) | 42.89 (5.41 to 339.81) | <0.001 | ||
| Gender | 0.964 | 0.981 | ||||||||
| Female | 5/4220 (1.97) | 265/2110 (253.08) | 118.62 (48.95 to 287.43) | <0.001 | 4/1130 (6.21) | 109/565 (457.11) | 68.09 (24.99 to 185.53) | <0.001 | ||
| Male | 0/2138 (0.00) | 42/1069 (82.71) | Cannot estimate | 0.985 | 0/698 (0.00) | 29/349 (196.26) | Cannot estimate | 0.992 | ||
AIHA, autoimmune haemolytic anaemia; ITP, immune thrombocytopenia; SLE, systemic lupus erythematosus.