Table 2

General features of anti-TIF1γ patients with and without anti-Sp4 autoantibodies

Anti-Sp4+
(n=26)
Anti-Sp4−
(n=35)
P valueTotal
(N=61)
Female sex81% (21)89% (31)0.585% (52)
Race
 White85% (22)86% (30)1.085% (52)
 Black0% (0)11% (4)0.17% (4)
 Other races15% (4)3% (1)0.28% (5)
Age of onset (years)43.0 (13.8)50.6 (15.3)0.0547.4 (15.1)
Time of follow-up (years)7.1 (4.3)4.8 (2.7)0.015.8 (3.7)
Number of visits per participant10.2 (7.7)10.9 (6.7)0.710.6 (7.1)
Cancer-associated myositis0% (0)14% (5)0.048% (5)
Death during follow-up0% (0)9% (3)0.35% (3)
Anti-Ro5215% (4)17% (6)1.016% (10)
Treatments
 Corticosteroids81% (21)71% (25)0.475% (46)
 Azathioprine27% (7)29% (10)0.928% (17)
 Methotrexate62% (16)54% (19)0.657% (35)
 Mycophenolate46% (12)46% (16)1.046% (28)
 Intravenous immunoglobulin38% (10)57% (20)0.149% (30)
 Rituximab12% (3)17% (6)0.715% (9)
  • Dichotomous variables were expressed as percentage (count) and continuous variables as mean (SD). Bivariate comparisons of continuous variables were made using Student’s t-test, while bivariate comparisons of dichotomous variables were made either using χ2 test or Fisher’s exact test, as appropriate.