Table 2

The top 10 SNPs associated with higher final mSASSS score (n=442*†)

SNPChr:PositionBetaGeneFunctionP value
rs19157352315:33 922 2081.127RYR3Exonic1.00×10−6
rs75182011:203 773 096−0.149ZC3H11AIntronic1.00×10−5
rs767891913:55 614 3200.580ERC2Intronic1.21×10−5
rs1174166652:44 606 3250.611CAMKMTIntronic2.36×10−5
rs13935805815:49 888 6270.976FAM227BIntronic2.78×10−5
rs750233617:78 281 770−0.160RNF213Intronic2.78×10−5
rs1445892509:140 218 9620.438EXD3Intronic3.17×10−5
rs169153319:101 135 2010.897GABBR2Intronic3.28×10−5
rs116869462:128 394 9550.182MYO7BExonic4.08×10−5
rs768386221:183 839 8560.727RGL1Intronic4.36×10−5
  • *Smoking data were available for 442 patients.

  • †Log(mSASSS+1) value was used.

  • Chr, chromosome; mSASSS, modified Stoke Ankylosing Spondylitis Spinal Score; SNP, single nucleotide polymorphism.