Table 1

Demographic and disease features of the patients with Takayasu arteritis and the comparators*

P value
Age, mean±SD years32.3±10.458.6±18.0<0.001
Female sex391 (84.6)246 (54.7)<0.001
Clinical features
 Angina56 (12.1)7 (1.6)<0.001
 Arm claudication233 (50.4)11 (2.4)<0.001
 Leg claudication88 (19.0)17 (3.8)<0.001
Vascular examination findings
 Arterial bruit263 (56.9)32 (7.1)<0.001
 Reduced or absent pulse in upper extremity309 (66.9)309 (66.9)<0.001
 Carotid artery with reduced pulse or tenderness171 (37.0)16 (3.6)<0.001
 Difference in systolic blood pressure ≥20 mm Hg between arms190 (41.1)16 (3.6)<0.001
Imaging findings
 1 affected arterial territory76 (16.5)36 (8.0)<0.001
 2 affected arterial territories114 (24.7)12 (2.7)<0.001
 ≥3 affected arterial territories89 (19.2)5 (1.1)<0.001
 Vasculitis affecting paired branch arteries140 (30.3)12 (2.7)<0.001
 Abdominal aorta involvement with renal or mesenteric artery involvement83 (18.0)5 (1.1)<0.001
  • *Except where indicated otherwise, values are the number (%).

  • †Diagnoses of comparators for the classification criteria for TAK included giant cell arteritis (n=151), Behçet’s disease (n=80), polyarteritis nodosa (n=39), clinically isolated aortitis (n=12), primary central nervous system vasculitis (n=11), large‐vessel vasculitis (LVV) that could not be subtyped (n=7) and other diseases that mimic LVV (n=150).

  • TAK, Takayasu arteritis.