Table 2

Significantly enriched cell type in autoimmune and allergic diseases

CategoryCell typeP value
BA (UKB)PO (UKB)BA (BBJ)
T cellT.4Mem.Sp 3.8×10-6 2.5×10-4 0.0015
T cellT.4Mem44h62l.Sp 1.3×10-5 1.9×10-4 5.3×10-4
Natural killer cellNKT.4-.Sp 3.1×10-5 4.6×10-5 0.0048
Natural killer cellNKT.4+.Lv 3.5×10-5 1.1×10-4 0.019
T cellLN.TR.14w.B6 4.4×10-5 3.6×10-5 7.4×10-4
T cellABD.TR.14w.B6 5.4×10-5 6.5×10-5 2.2×10-4
T cellT.4Mem44h62l.LN 1.4×10-4 5.6×10-4 0.0078
T cellCD4Control3.3×10-4 9.1×10-5 0.0013
T cellT.8Mem.Sp0.0100.0064 1.5×10-4
T cellT.8Eff.Tbet+.Sp.OT1.d6LisOVA0.0530.051 1.5×10-4
  • P values satisfying the threshold of 0.05/292 for Bonferroni multiple testing are shown in bold.

  • BA, bronchial asthma; BBJ, BioBank Japan; PO, pollinosis; UKB, UK Biobank.