Table 3

Outcome of the intention-to-treat analysis (n=100 in both groups)

Intervention	Flares	Group	Intervention visit				Total
Intervention	Flares	Group	I1	I2	I3	I4	Total
Stop medication		PREVENT-JIA	82	8	0	1	91
		BiKeR	9	10	3	3	25
	Within 3 months	PREVENT-JIA	4	1	0	0	5
	After stopping	BiKeR	3	3	0	0	6
	Within 6 months	PREVENT-JIA	15	1	0	0	16
	After stopping	BiKeR	1	1	1	1	4
	Within 9 months	PREVENT-JIA	8	2	0	1	11
	After stopping	BiKeR	0	3	0	0	3
	Within 12 months	PREVENT-JIA	7	2	0	0	9
	After stopping	BiKeR	0	1	1	0	2
	Total flares	PREVENT-JIA	34	6	0	1	41
	After stopping	BiKeR	4	8	2	1	15
Continue medication		PREVENT-JIA	18	4	3	1
		BiKeR	91	53	40	27
	Total flares	PREVENT-JIA	5	1	1	1	8
	Under therapy	BiKeR	23	7	10	7	47
Total flare rate after stopping medication		PREVENT-JIA					45% (41/91)
		BiKeR					60% (15/25)
Total flare rate in all patients		PREVENT-JIA					49% (49/100)
		BiKeR					62% (62/100)

BiKeR, Biologika in der Kinderrheumatologie ; JIA, juvenile idiopathic arthritis .