Results of interrupted time-series analysis of FSI/ASI rates, adjusting for age, gender, chronic obstructive pulmonary disease, Romano Charlson Comorbidity Index, diabetes, chronic kidney diseases, alcoholism, cancer, prior hospitalization with infection and socio-economic status at disease diagnosis year, using stepwise model selection
| Outcome | Parameter | RA | Non-RA | ||
|---|---|---|---|---|---|
| Unadj. Diff (95% CI) | Adj. Diff (95% CI) | Unadj. Diff (95% CI) | Adj. Diff (95% CI) | ||
| p-value | p-value | p-value | p-value | ||
| FSI | Trend | 0.63 (0.03, 1.22) 0.0441 | 0.68 (0.09, 1.27) 0.0292 | 0.08 (-0.08, 0.25) 0.3237 | 0.03 (-0.12, 0.19) 0.6728 |
| Level (1 year post-intervention) | 0.50 (-2.00, 2.99) 0.6989 | 0.31 (-1.88, 2.49) 0.7847 | 0.41 (-0.21, 1.03) 0.2041 | 0.26 (-0.24, 0.75) 0.3103 | |
| 5 years post-intervention | 3.01 (-0.85, 6.87) 0.1331 | 3.02 (-0.48, 6.52) 0.0986 | 0.75 (-0.24, 1.73) 0.1433 | 0.39 (-0.46, 1.25) 0.3721 | |
| ASI | Trend | 1.84 (0.83, 2.84) 0.0009 | 1.85 (0.81, 2.89) 0.0011 | 0.28 (0.04, 0.53) 0.0305 | 0.12 (-0.10, 0.34) 0.2877 |
| Level (1 year post-intervention) | -1.21 (-5.41, 3.00) 0.5763 | -1.44 (-5.44, 2.56) 0.4850 | 1.46 (0.42, 2.49) 0.0085 | 1.20 (0.38, 2.02) 0.0064 | |
| 5 years post-intervention | 6.14 (0.26, 12.01) 0.0466 | 5.97 (0.02, 11.93) 0.0560 | 2.60 (1.08, 4.12) 0.0017 | 1.69 (0.45, 2.92) 0.0109 | |