| Parameters | Group Аn=100 | Group Вn=58 | р | ||
|---|---|---|---|---|---|
| FVC1 M ± SD | 95.2±17.0 | Р=0.3 | 76.8±20.7 | P=0.0003 | |
| FVC1 M ± SD | 96.5±18.9 | 83.8±22.2 | |||
| Δ FVC %, SD’S [25%’S; 75%’S] | -0.7 [-5.8; 7,9] | 5.6 [-1.9;14.8] | 0.008 | ||
| DLCO 1, M ± SD | 62.6±19.9 | Р=0.08 | 46.4±18.3 | P=0.6 | |
| DLCO 2, M ± SD | 60.1±17.4 | 47.1±17.6 | |||
| Δ DLCO % | -1.7 [-5.9;3.3] | 1.25 [-4; 7.05] | 0.15 | ||
| mRss, 1 M ± SD | 5.6±5.3 | P=0.003 | 11.3±10.2 | P=0.000013 | |
| mRss, 2 M ± SD | 4.3±3.7 | 5.5±4.8 | |||
| Δ mRss, SD’S [25%’S; 75%’S] | 0 [-2;0] | -3 [-11;0] | 0.000031 | ||
| HAQ1 | 0.86±0.5 | P=0.9 | 1.14±0.8 | P=0.01 | |
| HAQ2 | 0.86±0.6 | 0.9±0.8 | |||
| EScSG 1, M ± SD | 1.64±1.2 | P=0.4 | 2.6± | P=0.0005 | |
| EScSG 2,M ± SD | 1.8±1.3 | 1.4± | |||
| Dose of glucocorticoids 1, mg | 8.8±4.8 | P=0.16 | 11.4±4.0 | P=0.002 | |
| Dose of glucocorticoids 2, mg | 8.1±3.7 | 9.1±2.9 | |||
| FVC increment by ≥10%, n/% | 16/16 | 17/29.3 | 0.04 | ||
| FVC decrement by ≥10% n/% | 14/14 | 4/6.7 | 0.18 | ||
| DLCO increment by ≥10%, n/% | 6/6 | 5/8.6 | 0.5 | ||
| DLCO decrement by ≥10% n/% | 14/14 | 5/8.6 | 0.3 | ||
1 = before treatment, 2 = after treatment; M ± SD = mean value and standard deviation; * = significant difference between the vales measured before and after the treatment