Table 1.

Multilevel logistic regression model: factors associated with unfavorable pregnancy outcome in women with RA.

Univariate analysesMultivariate analyses
Crude OR 95% CIpAdjusted OR 95% CIp
Age1.09 [1.01-1.19]0.0361.14 [1.02-1.28]0.019
BMI0.93 [0.83-1.04]0.1960.91 [0.77-1.08]0.204
Nulliparity4.18 [1.66-10.53]0.0036.16 [2.13-17.76]0.002
Smoking1.08 [0.29-3.36]0.9961.65 [0.37-7.22]0.141
Disease activity*1.06 [0.40-2.81]0.9110.98 [0.21-2.28]0.753
Corticosteroids**2.45 [1.05-5.68]0.0393.22 [1.09-9.57]0.038
Biologics**1.05 [0.11-3.54]0.5892.02 [0.70-4.12]0.194
  • * Moderate or severe disease activity at least once during pregnancy.

  • ** Use at least once during pregnancy